Multifunctional Nanocomposites in 3D Printing Technologies

A special issue of Nanomaterials (ISSN 2079-4991).

Deadline for manuscript submissions: closed (15 June 2018) | Viewed by 6272

Special Issue Editors


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Guest Editor
Department of Applied Science and Technology, Politecnico di Torino, C.so Duca degli Abruzzi 24, 10129 Turin, Italy
Interests: nanotechnologies applied to biological systems (in particular sensors, lab on chip, and organ on chip); graphene and 2D materials for energy and environment (solar cells, supercapacitors); nanomaterials for microelectronics; nanomaterials and nanostructures for CO2 trapping and reduction; multifunctional nanocomposites for 3D printing
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Guest Editor
Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, C.so Duca Degli Abruzzi 24, 10129 Torino, Italy
Interests: additive manufacturing at the micro scale; 3D printed devices; microelectronics; microsystems; micro-optics; advanced lithography; microsystems back end technologies

Special Issue Information

Dear Colleagues,

During the last few years, nanocomposites have become interesting for several industrial applications due to the possibility of adding functional properties by including nanostructures into a host material. Over the same period, 3D printing and additive manufacturing technologies have reached a good level of development with the possibility of being integrated in production lines for the manufacturing of complex components. The possibility of joining the functional properties of nanocomposites to 3D printing technologies is a present challenge, aiming to produce, in a single shot, complex components for industrial applications.

This Special Issue of Nanomaterials, “Multifunctional Nanocomposites in 3D Printing Technologies” aims to provide an overview on recent advances in the development of new materials, new printing technologies, and improvements to their performances.

Prof. Dr. Candido Fabrizio Pirri
Dr. Luciano Scaltrito
Guest Editors

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Keywords

  • Multifunctional nanocomposites
  • Multifunctional nanostructured polymeric materials
  • Multifunctional nanostructured ceramic materials
  • Multifunctional nanostructured metallic materials
  • Additive manufacturing
  • 3D printing technologies

Published Papers (1 paper)

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Research

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Article
Bioactive Molecules Release and Cellular Responses of Alginate-Tricalcium Phosphate Particles Hybrid Gel
by Dipankar Das, Sumi Bang, Shengmin Zhang and Insup Noh
Nanomaterials 2017, 7(11), 389; https://doi.org/10.3390/nano7110389 - 14 Nov 2017
Cited by 18 | Viewed by 5784
Abstract
In this article, a hybrid gel has been developed using sodium alginate (Alg) and α-tricalcium phosphate (α-TCP) particles through ionic crosslinking process for the application in bone tissue engineering. The effects of pH and composition of the gel on osteoblast cells (MC3T3) response [...] Read more.
In this article, a hybrid gel has been developed using sodium alginate (Alg) and α-tricalcium phosphate (α-TCP) particles through ionic crosslinking process for the application in bone tissue engineering. The effects of pH and composition of the gel on osteoblast cells (MC3T3) response and bioactive molecules release have been evaluated. At first, a slurry of Alg and α-TCP has been prepared using an ultrasonicator for the homogeneous distribution of α-TCP particles in the Alg network and to achieve adequate interfacial interaction between them. After that, CaCl2 solution has been added to the slurry so that ionic crosslinked gel (Alg-α-TCP) is formed. The developed hybrid gel has been physico-chemically characterized using Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and a swelling study. The SEM analysis depicted the presence of α-TCP micro-particles on the surface of the hybrid gel, while cross-section images signified that the α-TCP particles are fully embedded in the porous gel network. Different % swelling ratio at pH 4, 7 and 7.4 confirmed the pH responsiveness of the Alg-α-TCP gel. The hybrid gel having lower % α-TCP particles showed higher % swelling at pH 7.4. The hybrid gel demonstrated a faster release rate of bovine serum albumin (BSA), tetracycline (TCN) and dimethyloxalylglycine (DMOG) at pH 7.4 and for the grade having lower % α-TCP particles. The MC3T3 cells are viable inside the hybrid gel, while the rate of cell proliferation is higher at pH 7.4 compared to pH 7. The in vitro cytotoxicity analysis using thiazolyl blue tetrazolium bromide (MTT), bromodeoxyuridine (BrdU) and neutral red assays ascertained that the hybrid gel is non-toxic for MC3T3 cells. The experimental results implied that the non-toxic and biocompatible Alg-α-TCP hybrid gel could be used as scaffold in bone tissue engineering. Full article
(This article belongs to the Special Issue Multifunctional Nanocomposites in 3D Printing Technologies)
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