Submit to Special Issue Submit Abstract to Special Issue Review for Molecules Propose a Special Issue

Journal Menu

Journal Browser

► Journal Browser

Current Emerging Trends of Extraction and Encapsulation in Food

Special Issue Editors
Special Issue Information
Keywords
Published Papers

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Food Chemistry".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 6379

Share This Special Issue

Special Issue Editors

Dr. Seyed Mohammad Taghi Gharibzahedi

E-Mail Website
Guest Editor

Institute of Materials Science, Faculty of Engineering, Kiel University, 24143 Kiel, Germany
Interests: extraction; bio-functional materials; innovative nonthermal technologies; emulsification; colloids; encapsulation; food fortification; biopolymer; 3D‐printed biomaterials; novel foods
Special Issues, Collections and Topics in MDPI journals

Prof. Dr. Zeynep Altintas

E-Mail Website
Guest Editor

Institute of Materials Science, Faculty of Engineering, Kiel University, 24143 Kiel, Germany
Interests: bio-inspired materials; biosensors; biomedical engineering; molecularly imprinted polymers; molecular modelling; encapsulation; bioactive compounds
Special Issues, Collections and Topics in MDPI journals

Dr. Shahin Roohinejad

E-Mail
Guest Editor

Department of Food Science and Nutrition, University of Minnesota, St. Paul, MN 55108, USA
Interests: innovative food processing technologies; food functionality; food quality; encapsulation techniques; extraction; storage

Special Issue Information

Dear Colleagues,

There has been a growing interest in designing novel methodologies to extract and encapsulate bioactive compounds for developing therapeutic agents and functional foods owing to consumer concerns about the safety of synthetic constituents. The applied extraction and encapsulation techniques can greatly affect their process efficiency, physicochemical properties, and biological functions of healthy-functional ingredients and nutraceuticals. The current Special Issue comprises a wide spectrum of scientific topics related to the optimization of operating parameters in extraction and (micro- and nano-) encapsulation processes, the determination of the best formulation to achieve high-efficient bioactive-loaded capsules, the assessment of physicochemical and biological activities of extracts and capsules, kinetic studies, simulated gastrointestinal digestion evaluations, in vivo and in vitro toxicity, bioavailability, and bioaccessibility studies, microscopical and chemical profile analyses, and the appraisal of advanced analytical technologies to detect biomolecules in extracts and capsules during the process and storage such as chromatography and biosensor systems.

Therefore, this Special Issue aims to collect high-quality studies concerning current advances in the novel technologies of extraction and encapsulation of the high number of biologically active molecules to manufacture next-generation eco-friendly and sustainable food products. We cordially invite researchers and experts to participate in this forum to exchange up-to-date findings and innovative ideas related to cutting-edge research in the scientific area of extraction and encapsulation techniques.

Dr. Seyed Mohammad Taghi Gharibzahedi
Prof. Dr. Zeynep Altintas
Dr. Shahin Roohinejad
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

encapsulation techniques
extraction processes
bioactive compounds
complex coacervation
nanocarriers
controlled release
storage stability
food applications

Published Papers (5 papers)

Download All Papers

Order results

Result details

Show export options Show export options

Select all

Export citation of selected articles as:

Research

Jump to: Review

21 pages, 7798 KiB

Open AccessArticle

Process Optimization of Tinospora cordifolia Extract-Loaded Water in Oil Nanoemulsion Developed by Ultrasound-Assisted Homogenization

by Varisha Anjum, Uday Bagale, Ammar Kadi, Artem Malinin, Irina Potoroko, Amal H. Alharbi, Doaa Sami Khafaga, Marawa AlMetwally, Al-Seyday T. Qenawy, Areefa Anjum and Faraat Ali

Molecules 2024, 29(8), 1797; https://doi.org/10.3390/molecules29081797 - 16 Apr 2024

Viewed by 481

Abstract

Nanoemulsions are gaining interest in a variety of products as a means of integrating easily degradable bioactive compounds, preserving them from oxidation, and increasing their bioavailability. However, preparing stable emulsion compositions with the desired characteristics is a difficult task. The aim of this study was to encapsulate the Tinospora cordifolia aqueous extract (TCAE) into a water in oil (W/O) nanoemulsion and identify its critical process and formulation variables, like oil (27–29.4 mL), the surfactant concentration (0.6–3 mL), and sonication amplitude (40% to 100%), using response surface methodology (RSM). The responses of this formulation were studied with an analysis of the particle size (PS), free fatty acids (FFAs), and encapsulation efficiency (EE). In between, we have studied a fishbone diagram that was used to measure risk and preliminary research. The optimized condition for the formation of a stable nanoemulsion using quality by design was surfactant (2.43 mL), oil concentration (27.61 mL), and sonication amplitude (88.6%), providing a PS of 171.62 nm, FFA content of 0.86 meq/kg oil and viscosity of 0.597 Pa.s for the blank sample compared to the enriched TCAE nanoemulsion with a PS of 243.60 nm, FFA content of 0.27 meq/kg oil and viscosity of 0.22 Pa.s. The EE increases with increasing concentrations of TCAE, from 56.88% to 85.45%. The RSM response demonstrated that both composition variables had a considerable impact on the properties of the W/O nanoemulsion. Furthermore, after the storage time, the enriched TCAE nanoemulsion showed better stability over the blank nanoemulsion, specially the FFAs, and the blank increased from 0.142 to 1.22 meq/kg oil, while TCAE showed 0.266 to 0.82 meq/kg. Full article

(This article belongs to the Special Issue Current Emerging Trends of Extraction and Encapsulation in Food)

► Show Figures

Figure 1

15 pages, 6998 KiB

Open AccessArticle

Development of Anthocyanin-Rich Gel Beads from Colored Rice for Encapsulation and In Vitro Gastrointestinal Digestion

by Siriwan Soiklom, Wipada Siri-anusornsak, Krittaya Petchpoung and Wiratchanee Kansandee

Molecules 2024, 29(1), 270; https://doi.org/10.3390/molecules29010270 - 04 Jan 2024

Viewed by 863

Abstract

Colored rice anthocyanins are water-soluble natural pigments that can be used as an active ingredient in healthy food and pharmaceutical products. However, anthocyanin utilization is limited because of its instability. This work produced anthocyanin-rich gel beads from colored rice using a modified ionotropic gelation technique for encapsulation, and their efficacy was studied in vitro in the gastrointestinal tract. In total, 15 colored rice samples of three types (whole grain rice, ground rice, and ground germinated rice) were screened to identify the highest anthocyanin content. The anthocyanin content of the whole grain rice was significantly (p < 0.05) higher than it was in the ground and ground germinated rice. The sample with the highest anthocyanin content (1062.7 µg/g) was the black glutinous rice grain from Phrae, chosen based on its anthocyanin-rich crude extract. A new formula using a modified ionotropic gelation technique was prepared for the inclusion of the extract in gel beads. The results indicated that the incorporation of oil and wax significantly increased the encapsulation efficiency of the gel beads (% EE value of 85.43%) and improved the bioavailability of the active ingredient. Moreover, after simulated digestion, the release of anthocyanin and total phenolic content occurred more than five times. Scanning electron microscopy revealed that the surface of the gel beads was smooth. Furthermore, the presence of polyphenols and polysaccharides in the gel beads was confirmed using FTIR. The oil-wax-incorporated, anthocyanin-rich gel beads could be implemented for antioxidant delivery into the gastrointestinal tract to further improve healthy food and nutraceutical products. Full article

(This article belongs to the Special Issue Current Emerging Trends of Extraction and Encapsulation in Food)

► Show Figures

Graphical abstract

22 pages, 4931 KiB

Open AccessArticle

Effect of Inlet Air Temperature and Quinoa Starch/Gum Arabic Ratio on Nanoencapsulation of Bioactive Compounds from Andean Potato Cultivars by Spray-Drying

by Carlos A. Ligarda-Samanez, David Choque-Quispe, Elibet Moscoso-Moscoso, Lizeth M. Flores Pozo, Betsy S. Ramos-Pacheco, Henry Palomino-Rincón, Rodrigo J. Guzmán Gutiérrez and Diego E. Peralta-Guevara

Molecules 2023, 28(23), 7875; https://doi.org/10.3390/molecules28237875 - 30 Nov 2023

Cited by 2 | Viewed by 915

Abstract

Nanoencapsulation of native potato bioactive compounds by spray-drying improves their stability and bioavailability. The joint effect of the inlet temperature and the ratio of the encapsulant (quinoa starch/gum arabic) on the properties of the nanocapsules is unknown. The purpose of this study was to determine the best conditions for the nanoencapsulation of these compounds. The effects of two inlet temperatures (96 and 116 °C) and two ratios of the encapsulant (15 and 25% w/v) were evaluated using a factorial design during the spray-drying of native potato phenolic extracts. During the study, measurements of phenolic compounds, flavonoids, anthocyanins, antioxidant capacity, and various physical and structural properties were carried out. Higher inlet temperatures increased bioactive compounds and antioxidant capacity. However, a higher concentration of the encapsulant caused the dilution of polyphenols and anthocyanins. Instrumental analyses confirmed the effective encapsulation of the nuclei in the wall materials. Both factors, inlet temperature, and the encapsulant ratio, reduced the nanocapsules’ humidity and water activity. Finally, the ideal conditions for the nanoencapsulation of native potato bioactive compounds were determined to be an inlet temperature of 116 °C and an encapsulant ratio of 15% w/v. The nanocapsules obtained show potential for application in the food industry. Full article

(This article belongs to the Special Issue Current Emerging Trends of Extraction and Encapsulation in Food)

► Show Figures

Graphical abstract

Review

Jump to: Research

36 pages, 8597 KiB

Open AccessReview

Recent Advances in Dietary Sources, Health Benefits, Emerging Encapsulation Methods, Food Fortification, and New Sensor-Based Monitoring of Vitamin B₁₂: A Critical Review

by Seyed Mohammad Taghi Gharibzahedi, Maryam Moghadam, Jonas Amft, Aysu Tolun, Gauri Hasabnis and Zeynep Altintas

Molecules 2023, 28(22), 7469; https://doi.org/10.3390/molecules28227469 - 07 Nov 2023

Cited by 1 | Viewed by 2248

Abstract

In this overview, the latest achievements in dietary origins, absorption mechanism, bioavailability assay, health advantages, cutting-edge encapsulation techniques, fortification approaches, and innovative highly sensitive sensor-based detection methods of vitamin B₁₂ (VB₁₂) were addressed. The cobalt-centered vitamin B is mainly found in animal products, posing challenges for strict vegetarians and vegans. Its bioavailability is highly influenced by intrinsic factor, absorption in the ileum, and liver reabsorption. VB₁₂ mainly contributes to blood cell synthesis, cognitive function, and cardiovascular health, and potentially reduces anemia and optic neuropathy. Microencapsulation techniques improve the stability and controlled release of VB₁₂. Co-microencapsulation of VB₁₂ with other vitamins and bioactive compounds enhances bioavailability and controlled release, providing versatile initiatives for improving bio-functionality. Nanotechnology, including nanovesicles, nanoemulsions, and nanoparticles can enhance the delivery, stability, and bioavailability of VB₁₂ in diverse applications, ranging from antimicrobial agents to skincare and oral insulin delivery. Staple food fortification with encapsulated and free VB₁₂ emerges as a prominent strategy to combat deficiency and promote nutritional value. Biosensing technologies, such as electrochemical and optical biosensors, offer rapid, portable, and sensitive VB₁₂ assessment. Carbon dot-based fluorescent nanosensors, nanocluster-based fluorescent probes, and electrochemical sensors show promise for precise detection, especially in pharmaceutical and biomedical applications. Full article

(This article belongs to the Special Issue Current Emerging Trends of Extraction and Encapsulation in Food)

► Show Figures

Figure 1

17 pages, 1275 KiB

Open AccessReview

A Brief Review on the Electrohydrodynamic Techniques Used to Build Antioxidant Delivery Systems from Natural Sources

by Sílvia Castro Coelho and Berta Nogueiro Estevinho

Molecules 2023, 28(8), 3592; https://doi.org/10.3390/molecules28083592 - 20 Apr 2023

Cited by 4 | Viewed by 1206

Abstract

Extracts from plants have been one of the main sources of antioxidants, namely polyphenols. The associated drawbacks, such as instability against environmental factors, low bioavailability, and loss of activity, must be considered during microencapsulation for a better application. Electrohydrodynamic processes have been investigated as promising tools to fabricate crucial vectors to minimize these limitations. The developed microstructures present high potential to encapsulate active compounds and for controlling their release. The fabricated electrospun/electrosprayed structures present different benefits when compared with structures developed by other techniques; they present a high surface-area-to-volume ratio as well as porosity, great materials handling, and scalable production—among other advantages—which make them able to be widely applied in different fields, namely in the food industry. This review presents a summary of the electrohydrodynamic processes, main studies, and their application. Full article

(This article belongs to the Special Issue Current Emerging Trends of Extraction and Encapsulation in Food)

► Show Figures

Journal Menu

Journal Browser

Current Emerging Trends of Extraction and Encapsulation in Food

Share This Special Issue

Special Issue Editors

Special Issue Information

Keywords

Published Papers (5 papers)

Research

Review

Further Information

Guidelines

MDPI Initiatives

Follow MDPI