Survival, Persistence and Resistance in Salmonella

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".

Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 12050

Special Issue Editor


E-Mail Website
Guest Editor
Quadram Institute Bioscience, Norwich, UK
Interests: niche adaptation; genome structure; environmental persistence

Special Issue Information

The aim of this Special Issue is to present a collection of articles that provide an up-to-date view of the environmental survival, persistence, and antimicrobial resistance associated with Salmonella infections.

With the advent of metagenomics and genome sequencing of isolates, the typing of Salmonella is becoming more precise. This allows the comparison of strain types found in different niches and the spread of outbreak strains. The ability to survive in harsh environments is a major property allowing the dissemination of Salmonella, and as antibiotic resistance expands, the strains in which resistance is carried, disseminated, and transmitted from person to person is key.

Articles are encouraged that fit one or more of these areas:

  • Survival: Which Salmonella are found where, including strains of Salmonella found in different environments, particularly from LMICs and/or strains that spread widely.
  • Persistence: How Salmonella persist in the gut or the environment. Descriptions of the genes, plasmids, mobile genetic elements involved, and/or the molecular mechanisms (including biofilm formation) underlying survival.
  • Resistance: Reports of AMR in clinically important Salmonella and/or environmental reservoirs

Dr. Gemma C. Langridge
Guest Editor

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Keywords

  • Salmonella
  • persistence
  • environment
  • niche
  • biofilm
  • detection
  • adaptation
  • chronic
  • antimicrobial resistance

Published Papers (2 papers)

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Research

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16 pages, 367 KiB  
Article
Virulence and Antimicrobial Resistance Profiles of Salmonella enterica Serovars Isolated from Chicken at Wet Markets in Dhaka, Bangladesh
by Nure Alam Siddiky, Md Samun Sarker, Md. Shahidur Rahman Khan, Ruhena Begum, Md. Ehsanul Kabir, Md. Rezaul Karim, Md. Tanvir Rahman, Asheak Mahmud and Mohammed A. Samad
Microorganisms 2021, 9(5), 952; https://doi.org/10.3390/microorganisms9050952 - 28 Apr 2021
Cited by 24 | Viewed by 4885
Abstract
Virulent and multi drug resistant (MDR) Salmonellaenterica is a foremost cause of foodborne diseases and had serious public health concern globally. The present study was undertaken to identify the pathogenicity and antimicrobial resistance (AMR) profiles of Salmonellaenterica serovars recovered from chicken [...] Read more.
Virulent and multi drug resistant (MDR) Salmonellaenterica is a foremost cause of foodborne diseases and had serious public health concern globally. The present study was undertaken to identify the pathogenicity and antimicrobial resistance (AMR) profiles of Salmonellaenterica serovars recovered from chicken at wet markets in Dhaka, Bangladesh. A total of 870 cecal contents of broiler, sonali, and native chickens were collected from 29 wet markets. The overall prevalence of S. Typhimurium, S. Enteritidis, and untyped Salmonella spp., were found to be 3.67%, 0.57%, and 1.95% respectively. All isolates were screened by polymerase chain reaction (PCR) for eight virulence genes, namely invA, agfA, IpfA, hilA, sivH, sefA, sopE, and spvC. S. Enteritidis isolates carried all virulence genes whilst S. Typhimurium isolates carried six virulence genes except sefA and spvC. A diverse phenotypic and genotypic AMR pattern was found. Harmonic descending trends of resistance patterns were observed among the broiler, sonali, and native chickens. Interestingly, virulent and MDR Salmonella enterica serovars were found in native chicken, although antimicrobials were not used in their production cycle. The research findings anticipate that virulent and MDR Salmonella enterica are roaming in the wet markets which can easily anchor to the vendor, consumers, and in the food chain. Full article
(This article belongs to the Special Issue Survival, Persistence and Resistance in Salmonella)

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10 pages, 1364 KiB  
Brief Report
Emergence of Resistance to Fluoroquinolones and Third-Generation Cephalosporins in Salmonella Typhi in Lahore, Pakistan
by Farhan Rasheed, Muhammad Saeed, Nabil-Fareed Alikhan, David Baker, Mohsin Khurshid, Emma V. Ainsworth, A. Keith Turner, Ambereen Anwar Imran, Muhammad Hidayat Rasool, Muhammad Saqalein, Muhammad Atif Nisar, Muhammad Fayyaz ur Rehman, John Wain, Muhammad Yasir, Gemma C. Langridge and Aamer Ikram
Microorganisms 2020, 8(9), 1336; https://doi.org/10.3390/microorganisms8091336 - 1 Sep 2020
Cited by 30 | Viewed by 6581
Abstract
Extensively drug-resistant (XDR) Salmonella Typhi has been reported in Sindh province of Pakistan since 2016. The potential for further spread is of serious concern as remaining treatment options are severely limited. We report the phenotypic and genotypic characterization of 27 XDR S. [...] Read more.
Extensively drug-resistant (XDR) Salmonella Typhi has been reported in Sindh province of Pakistan since 2016. The potential for further spread is of serious concern as remaining treatment options are severely limited. We report the phenotypic and genotypic characterization of 27 XDR S. Typhi isolated from patients attending Jinnah Hospital, Lahore, Pakistan. Isolates were identified by biochemical profiling; antimicrobial susceptibility was determined by a modified Kirby–Bauer method. These findings were confirmed using Illumina whole genome nucleotide sequence data. All sequences were compared to the outbreak strain from Southern Pakistan and typed using the S. Typhi genotyping scheme. All isolates were confirmed by a sequence analysis to harbor an IncY plasmid and the CTX-M-15 ceftriaxone resistance determinant. All isolates were of the same genotypic background as the outbreak strain from Sindh province. We report the first emergence of XDR S. Typhi in Punjab province of Pakistan confirmed by whole genome sequencing. Full article
(This article belongs to the Special Issue Survival, Persistence and Resistance in Salmonella)
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