One Health Approach to Fungal and Parasitic Diseases: Transmission, Resistance and Therapy

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Parasitology".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 4350

Special Issue Editor


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Guest Editor
1. Department of Medical Mycology and Parasitology, Nantes University Hospital and EA1155 IICiMed, Nantes, France
2. Institut de Recherche en Santé2 (IRS2) University of Nantes, 44000 Nantes, France
Interests: microbiology; fungi; Leishmania; resistance; antifungal compounds; host-pathogen interaction; environment; One Health
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Special Issue Information

Dear Colleagues,

The One Health approach ensures that human, animal, and environmental microbiological questions are evaluated in an integrated manner so as to provide a more comprehensive understanding of the problem of pathogen transmission and resistance. This concept is not only relevant for human and veterinary medicine, but also for all scientific health-related disciplines. We can definitively consider that this approach can accelerate synergistic and efficient actions.

Because numerous protozoal (Leishmaniasis, Trypanosomiasis, etc.) and helminthic (Schistosomiasis, Fascioliasis, etc.) diseases are zoonotic or vector-borne, parasites are obviously excellent models for the One Health approach. When it comes to the field of mycology (Aspergillus, Cryptococcus, Dermatophytes, Fusarium, etc.), researchers must still investigate this multidisciplinary initiative as recently described for azole-environmental resistance. Human and veterinary diseases remain topics where the multidisciplinary effort experience must be shared with all researchers.

In this Special Issue of Microorganisms dedicated to the One Health approach to fungal and parasitic diseases, we invite you to send your research articles dedicated exclusively on fundamental data concerning microorganisms implicated in human and animal mycology and in parasitic diseases from a One Health angle. Antimicrobial resistance and therapeutic aspects of the diseases are also welcome.

Prof. Patrice Le Pape
Guest Editor

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Keywords

  • One Health
  • filamentous fungi
  • yeast
  • parasite
  • vectors
  • environment

Published Papers (1 paper)

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Review

18 pages, 1345 KiB  
Review
Prototheca Infections and Ecology from a One Health Perspective
by Balázs Libisch, Carine Picot, Andrés Ceballos-Garzon, Monika Moravkova, Marcela Klimesová, Gábor Telkes, Shih-Te Chuang and Patrice Le Pape
Microorganisms 2022, 10(5), 938; https://doi.org/10.3390/microorganisms10050938 - 29 Apr 2022
Cited by 16 | Viewed by 3527
Abstract
Prototheca microalgae were only recognized as pathogens of both humans and animals in the 1960s; however, since then, these microbes have been drawing increasing interest in both human and veterinary medicine. The first human outbreak of protothecosis in a tertiary care chemotherapy ward [...] Read more.
Prototheca microalgae were only recognized as pathogens of both humans and animals in the 1960s; however, since then, these microbes have been drawing increasing interest in both human and veterinary medicine. The first human outbreak of protothecosis in a tertiary care chemotherapy ward in 2018 further highlighted the need to understand in more depth and detail their ecology, etiology, pathogenesis and routes of transmission between different hosts, environments and habitats from a One Health perspective. Protothecal infections have been reported in a growing number of cattle herds around the world in recent decades, and Prototheca has become an important bovine mastitis pathogen in certain countries and regions. The survival of Prototheca in the environment and its ability to spread in the herd pose a serious challenge to the management of infected dairy farms. Prevention of the disease is particularly important, as there is no effective and reliable treatment for it and the chances of self-healing are minimal. Therefore, the development of more effective drugs is needed for the treatment of human and animal protothecosis. The prudent use of antibiotics and their replacement by alternative or preventive measures, when possible, may further contribute to the control of protothecal infections. Full article
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