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Journals
Microorganisms
Special Issues
Trends in Viral Zoonotic and Zooanthroponotic Diseases
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Trends in Viral Zoonotic and Zooanthroponotic Diseases

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".

Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 3602

Special Issue Editors

Prof. Dr. Muhammad Munir

E-Mail Website
Guest Editor
Division of Biomedical and Life Science, Lancaster University, Lancaster LA1 4YG, UK
Interests: zoonotic viruses; virus pathogenesis; host responses; influenza viruses; coronaviruses
Special Issues, Collections and Topics in MDPI journals
Dr. Mohammed Rohaim

E-Mail Website
Co-Guest Editor
1. Biomedical and Life Sciences, Lancaster University, Lancaster LA1 4YG, UK
2. Department of Virology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt
Interests: influenza viruses; coronaviruses, pathogenesis and transmission; antivirals; vaccines; animal models; viral zoonosis; emerging and re-emerging viruses; host-pathogen interactions; innate immunity and virus evolution
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Transmission of a pathogen from animal to human (zoonosis) and human to animal (zooanthroponosis) is currently a leading threat for both veterinary and human public health. This threat can be testified by the fact that ~60% of emerging infectious diseases are of zoonotic origin and ~70% of these originate from wildlife. The importance of studying zoonotic and zooanthroponotic diseases is further highlighted by the emergence of multiple variants of SARS-CoV-2. A range of animal species have been verified for SARS-COV-2 and other zoonotic infections either in vitro or in vivo. However, the molecular bases of such a broad host spectrum of these infections have remained elusive.

For this Special Issue, we are seeking the submission of manuscripts on any aspect of zoonotic and zoonanthroponotic viral diseases. We welcome both original research articles and comprehensive review papers. The papers in this Special Issue will be published via our open access platform after a thorough peer review, a process which will benefit both our authors and readers.

As evidenced by the keywords list, the fields to be included in this Special Issue have been broadened to best represent the scope of the issue while creating more opportunities for international research contributions. We aim to bring forward cutting-edge research and critical analysis to provide a foundation on the possible faunal virus persistence in animals and their implications in future threats of viral transmission from animal to human or human to animal.

Dr. Muhammad Munir
Dr. Mohammed Rohaim
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • zoonotic diseases
  • zoonoses and public health
  • veterinary medicine
  • infectious viral diseases
  • One Health and EcoHealth
  • virology
  • epidemiology
  • control and prevention of zoonotic viral disease
  • disease ecology
  • disease vectors
  • disease detection and diagnostics
  • disease modelling

Published Papers (2 papers)

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Research

17 pages, 4114 KiB  
Article
The Emergence and Dynamics of Tick-Borne Encephalitis Virus in a New Endemic Region in Southern Germany
by Daniel Lang, Lidia Chitimia-Dobler, Malena Bestehorn-Willmann, Alexander Lindau, Marco Drehmann, Gabriele Stroppel, Helga Hengge, Ute Mackenstedt, Klaus Kaier, Gerhard Dobler and Johannes Borde
Microorganisms 2022, 10(11), 2125; https://doi.org/10.3390/microorganisms10112125 - 27 Oct 2022
Cited by 5 | Viewed by 1247
Abstract
Tick-borne encephalitis (TBE) is the most important viral tick-borne infection in Europe and Asia. It is emerging in new areas. The mechanisms of emergence are fairly unknown or speculative. In the Ravensburg district in southern Germany, TBE emerged, mainly over the last five [...] Read more.
Tick-borne encephalitis (TBE) is the most important viral tick-borne infection in Europe and Asia. It is emerging in new areas. The mechanisms of emergence are fairly unknown or speculative. In the Ravensburg district in southern Germany, TBE emerged, mainly over the last five years. Here, we analyzed the underlying epidemiology in humans. The resulting identified natural foci of the causal TBE virus (TBEV) were genetically characterized. We sampled 13 potential infection sites at these foci and detected TBEV in ticks (Ixodes ricinus) at eight sites. Phylogenetic analysis spurred the introduction of at least four distinct TBEV lineages of the European subtype into the Ravensburg district over the last few years. In two instances, a continuous spread of these virus strains over up to 10 km was observed. Full article
(This article belongs to the Special Issue Trends in Viral Zoonotic and Zooanthroponotic Diseases)
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14 pages, 2486 KiB  
Article
The Immune Efficacy of Inactivated Pseudorabies Vaccine Prepared from FJ-2012ΔgE/gI Strain
by Qiu-Yong Chen, Xue-Min Wu, Yong-Liang Che, Ru-Jing Chen, Bo Hou, Chen-Yan Wang, Long-Bai Wang and Lun-Jiang Zhou
Microorganisms 2022, 10(10), 1880; https://doi.org/10.3390/microorganisms10101880 - 21 Sep 2022
Cited by 3 | Viewed by 1409
Abstract
An emerging pseudorabies virus (PRV) variant has been reported on Bartha-K61-vaccinated farms since 2011, causing great economic losses to China’s swine-feeding industry. In this study, two vaccines, FJ-2012ΔgE/gI-GEL02 and FJ-2012ΔgE/gI-206VG, were administered to piglets for immune efficacy investigation. Humoral immunity response, clinical signs, [...] Read more.
An emerging pseudorabies virus (PRV) variant has been reported on Bartha-K61-vaccinated farms since 2011, causing great economic losses to China’s swine-feeding industry. In this study, two vaccines, FJ-2012ΔgE/gI-GEL02 and FJ-2012ΔgE/gI-206VG, were administered to piglets for immune efficacy investigation. Humoral immunity response, clinical signs, survival rate, tissue viral load, and pathology were assessed in piglets. The results showed that both vaccines were effective against the PRV FJ-2012 challenge, the piglets all survived while developing a high level of gB-specific antibody and neutralizing antibody, the virus load in tissue was alleviated, and no clinical PR signs or pathological lesions were displayed. In the unimmunized challenged group, typical clinical signs of pseudorabies were observed, and the piglets all died at 7 days post-challenge. Compared with commercial vaccines, the Bartha-K61 vaccine group could not provide full protection, which might be due to a lower vaccine dose; the inactivated vaccine vPRV* group piglets survived, displaying mild clinical signs. The asterisk denotes inactivation. These results indicate that FJ-2012ΔgE/gI-GEL02 and FJ-2012ΔgE/gI-206VG were effective and could be promising vaccines to control or eradicate the new PRV epidemic in China. Full article
(This article belongs to the Special Issue Trends in Viral Zoonotic and Zooanthroponotic Diseases)
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