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Microorganisms
Special Issues
Skin Microbiome, a Long Story of Clinical Trials 2.0
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Skin Microbiome, a Long Story of Clinical Trials 2.0

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: closed (31 July 2022) | Viewed by 2198

Special Issue Editor

Dr. Lionel Breton

E-Mail Website
Guest Editor
Former Scientific Director L’Oreal Research, Cilia Consulting CEO, IDEC Therapeutic (Telostim.com) CSO, Paris, France
Interests: immunology; pharmacology; neurobiology; skin physiology; skin microbiome
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our previous special issue "Skin Microbiome, a Long Story of Clinical Trials".

The scientific community continues to demonstrate the functional role of the human gut and skin microbiome as an inspirational source for future therapeutics. Despite the huge potential offered by these discoveries in providing health in the long run, future therapeutics are still limited by the challenges in obtaining relevant clinical outcomes. In recent years, skin has evolved as one of the most extensively described tissue regarding microbiome diversities linked to host physiology, age, environmental exposure, and diseases. Moreover, the role of the skin microbiome has been validated by clinical results with respect to atopic dermatitis, psoriasis, acne, and seborrheic dermatitis.

This Special Issue gathers recent research and new results of the clinical evaluation of skin microbiome-based treatments. It will serve as guidance for scientists from the biopharmaceutical and academic community to investigate the causal role of the skin microbiota in disease and to create a new generation of microbiome-targeted therapeutics with predictable modes of action and consistent clinical outcomes.

Dr. Lionel Breton
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

11 pages, 10842 KiB  
Article
Effect of Solar Radiation on Skin Microbiome: Study of Two Populations
by Nurit Harel, Leah Reshef, Dvora Biran, Sarah Brenner, Eliora Z. Ron and Uri Gophna
Microorganisms 2022, 10(8), 1523; https://doi.org/10.3390/microorganisms10081523 - 27 Jul 2022
Cited by 4 | Viewed by 1766
Abstract
Here, we examined the skin microbiome of two groups of healthy volunteers living on the Mediterranean coast with different exposures to sun radiation. One group, exposed to the sun in the summer, was compared with a group covered with clothing throughout the year. [...] Read more.
Here, we examined the skin microbiome of two groups of healthy volunteers living on the Mediterranean coast with different exposures to sun radiation. One group, exposed to the sun in the summer, was compared with a group covered with clothing throughout the year. The seasonal effects on the skin microbiome of three body sites were determined before and after summer. Surprisingly, at the phyla level, there were no significant differences in microbiome diversity between the groups. Furthermore, within each group, there were no significant seasonal differences in high-abundance species at any of the sampling sites. These results suggest that the skin microbiome, developed over years, remains stable even after several months of exposure to summer weather, direct sunlight and humidity. However, in the group exposed to the sun during the summer months, there were significant differences in low-abundance species in sun-exposed areas of the skin (the inner and outer arm). These subtle changes in low-abundance species are interesting, and their effect on skin physiology should be studied further. Full article
(This article belongs to the Special Issue Skin Microbiome, a Long Story of Clinical Trials 2.0)
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