Dampness and Mold Hypersensitivity Syndrome

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Public Health Microbiology".

Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 6312

Special Issue Editors


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Guest Editor
Kruunuhaka Medical Center, Kaisaniemenkatu 1Ba, 00 180 Helsinki, Finland
Interests: multiple chemical sensitivity; mold-related disease; sensitivity to electromagnetic fields; diagnostics; biomarkers

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Guest Editor
Medical Advisor to Mymycolab LLC, Land O' Lakes, FL, USA
Interests: mycotoxins; neurotoxicity from mycotoxins; mast cell activation from mycotoxins; inflammation from molds/mycotoxins; mycotoxicosis; mycotoxin antibodies
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Special Issue Information

Dear Colleagues,

Dampness and mold hypersensitivity syndrome (DMHS) is a chronic debilitating condition that occurs after cumulative or prolonged exposure to indoor air dampness microbiota (DM). It is a worldwide problem, but it is often neglected, overlooked, and denied. At present, there is no single biomarker to diagnose this illness. Only respiratory symptoms such as allergic rhinitis, cough, the onset of new asthma or exacerbation of diagnosed asthma have been linked to the exposure to DM. However, many patients complain about non-respiratory symptoms such as fatigue, symptoms of the central nervous system, and dysautonomia. Multiple chemical sensitivity and even sensitivity to electromagnetic fields can develop at prolonged exposure. The aim of this Special issue is to update our current knowledge on the studies of indoor air, clinical presentations of the DMHS, diagnostics, and treatment. The final goal is to promote better recognition of this disorder and improve quality of life of the sufferers.

Dr. Tamara Tuuminen
Dr. Andrew W. Campbell
Guest Editor

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Keywords

  • dampness and mold hypersensitivity syndrome
  • multiple chemical sensitivity
  • dampness microbiota
  • mold-related disease
  • indoor air
  • asthma
  • molds
  • allergic rhinitis
  • chronic fatigue syndrome
  • neurological symptoms
  • dysautonomia

Published Papers (1 paper)

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Research

20 pages, 9345 KiB  
Article
Bioreactivity, Guttation and Agents Influencing Surface Tension of Water Emitted by Actively Growing Indoor Mould Isolates
by Maria A. Andersson, Johanna Salo, Orsolya Kedves, László Kredics, Irina Druzhinina, Jarek Kurnitski and Heidi Salonen
Microorganisms 2020, 8(12), 1940; https://doi.org/10.3390/microorganisms8121940 - 07 Dec 2020
Cited by 12 | Viewed by 3417
Abstract
The secretion of metabolites in guttation droplets by indoor moulds is not well documented. This study demonstrates the guttation of metabolites by actively growing common indoor moulds. Old and fresh biomasses of indoor isolates of Aspergillus versicolor, Chaetomium globosum, Penicillium expansum [...] Read more.
The secretion of metabolites in guttation droplets by indoor moulds is not well documented. This study demonstrates the guttation of metabolites by actively growing common indoor moulds. Old and fresh biomasses of indoor isolates of Aspergillus versicolor, Chaetomium globosum, Penicillium expansum, Trichoderma atroviride, T. trixiae, Rhizopus sp. and Stachybotrys sp. were compared. Metabolic activity indicated by viability staining and guttation of liquid droplets detected in young (<3 weeks old) biomass were absent in old (>6 months old) cultures consisting of dehydrated hyphae and dormant conidia. Fresh (<3 weeks old) biomasses were toxic more than 10 times towards mammalian cell lines (PK-15 and MNA) compared to the old dormant, dry biomasses, when calculated per biomass wet weight and per conidial particle. Surfactant activity was emitted in exudates from fresh biomass of T. atroviride, Rhizopus sp. and Stachybotrys sp. Surfactant activity was also provoked by fresh conidia from T. atroviride and Stachybotrys sp. strains. Water repealing substances were emitted by cultures of P. expansum, T. atroviride and C. globosum strains. The metabolic state of the indoor fungal growth may influence emission of liquid soluble bioreactive metabolites into the indoor air. Full article
(This article belongs to the Special Issue Dampness and Mold Hypersensitivity Syndrome)
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