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Journals
Microorganisms
Special Issues
Molecular Epidemiology of Leishmaniasis
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Molecular Epidemiology of Leishmaniasis

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Parasitology".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 1070

Special Issue Editor

Dr. Isabel Mauricio

E-Mail Website
Guest Editor
Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, 1349-008 Lisbon, Portugal
Interests: helminths; leishmaniasis; genetic diversity; genotyping; molecular epidemiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The molecular epidemiology of leishmaniasis is a developing field that has been revolutionised by the emergence of genomic epidemiology and population genetics, as well as deep sequencing applications to study population diversity within hosts, which also inform the development of improved diagnostic and genotyping methods.

This Special Issue will accept Original Research Articles and Reviews that cover all aspects related to the molecular epidemiology of leishmaniasis, including, but not limited to, genomic epidemiology, the development, application, and validation of improved genetic markers in diagnosis and genotyping, and studies that use molecular markers and genome sequences to elucidate transmission, association with clinical presentation, new reservoir hosts or vectors, and the taxonomy of leishmaniasis.

Dr. Isabel Mauricio
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • leishmaniasis
  • molecular epidemiology
  • genomic epidemiology
  • genetic markers
  • transmission
  • molecular diagnosis
  • molecular taxonomy

Published Papers (1 paper)

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Research

12 pages, 649 KiB  
Article
Coinfection with Leishmania infantum and Toxoplasma gondii in Domestic Cats from a Region with a High Prevalence of Feline Immunodeficiency Virus
by José Artur Brilhante Bezerra, Amanda Haisi, Gabrielle dos Santos Rocha, Suellen Gonçalves Lima, Arthur Willian de Lima Brasil, Klívio Loreno Raulino Tomaz, Felipe Fornazari, Helio Langoni, João Pessoa Araújo Junior, João Marcelo Azevedo de Paula Antunes and Sérgio Santos de Azevedo
Microorganisms 2024, 12(1), 71; https://doi.org/10.3390/microorganisms12010071 - 29 Dec 2023
Cited by 1 | Viewed by 879
Abstract
The aim of this study was to investigate the coinfection of feline retroviruses (feline immunodeficiency virus—FIV, and the feline leukemia virus—FeLV) with Leishmania infantum and Toxoplasma gondii and the factors associated with these pathogens in domestic cats from Mossoró, a city endemic for [...] Read more.
The aim of this study was to investigate the coinfection of feline retroviruses (feline immunodeficiency virus—FIV, and the feline leukemia virus—FeLV) with Leishmania infantum and Toxoplasma gondii and the factors associated with these pathogens in domestic cats from Mossoró, a city endemic for canine and human leishmaniasis situated in the semiarid region of Northeast Brazil. Blood samples from 120 cats were collected, and an epidemiological questionnaire was applied to investigate the risk factors associated with the infections. Retroviruses, L. infantum, and T. gondii infections were assessed using a point-of-care ELISA and quantitative PCR (qPCR), indirect fluorescent antibody test (IFAT) and qPCR, and IFAT, respectively. The overall seroprevalences observed were 35% (95% CI = 27.0–43.8%) for FIV, 0.8% (95% CI = 0.1–4.5%) for FeLV, 25.8% (95% CI = 18.8–34.3%) for T. gondii, and 4.2% (95% CI = 1.7–9.3%) for L. infantum. Coinfection with FIV and L. infantum was observed in 2.5% (3/120) of the assessed cats, while 12.5% (15/120) were coinfected with FIV and T. gondii. No significant association was found among the investigated agents (p > 0.05). The factors associated with FIV infection in the multivariable analysis were male sex and age above 78 months. The findings of this study demonstrated a high rate of FIV infection in cats from the Brazilian semiarid region and the exposure of these animals to zoonotic and opportunistic agents. Due to the immunosuppressive potential of FIV, cats infected with this retrovirus should be screened for coinfections with L. infantum and T. gondii, and preventative measures should be adopted. Full article
(This article belongs to the Special Issue Molecular Epidemiology of Leishmaniasis)
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