Microbiota of Insect Vectors

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Parasitology".

Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 1005

Special Issue Editors


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Guest Editor
UNESP—Biotechnology Institute and Biosciences Institute, Sao Paulo State University, Botucatu 18618-689, Brazil
Interests: mosquito population genetics; metagenomics; transcriptomics

E-Mail Website
Guest Editor
1. Department of Epidemiology, School of Public Health, University of São Paulo, São Paulo 01246-904, Brazil
2. Biotechnology Institute, Sao Paulo State University, Botucatu 18618-689, Brazil
Interests: metagenomics; vectors population genetics; molecular epidemiology

Special Issue Information

Dear Colleagues,

Insects serve as vectors of many pathogens of public health importance, harboring a diversity of microbes from bacteria to fungi that are often found in close proximity to the pathogens that the vectors transmit. The microbiota associated with insects play important roles in vector physiology, such as digestion, nutrition and innate immune modulation. Moreover, the intimate relationship that often exists between some of these microbes and their arthropod hosts supports investigations into their use in vector-borne disease control strategies, especially when a microbial symbiont is identified. The application of microbial symbionts to reduce vector competence is a novel approach to controlling the spread of arthropod-transmitted pathogens, with most of the examples coming from mosquitoes that are refractory to Plasmodium infection depending on the load and composition of bacteria found in their guts. Another approach, paratransgenesis, makes use of this information but goes a step further to effectively target the pathogen. Through the genetic modification of bacterial symbionts to produce anti-pathogen molecules in the proper tissues or compartments of the insect, vector competence for pathogens can be reduced. This Special Issue encourages the submission of any paper dealing with the current advances in the understanding of vector–microbiota–pathogen tripartite interactions and also the future perspectives on the application of microorganisms as novel control strategies.

Prof. Dr. Paulo Eduardo Martins Ribolla
Dr. Diego Peres Alonso
Guest Editors

Manuscript Submission Information

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Keywords

  • 16s metagenomics
  • novel control strategies
  • paratransgenesis
  • arthropod-transmitted pathogens
  • vector-borne diseases

Published Papers (1 paper)

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Research

13 pages, 1193 KiB  
Article
Wolbachia and Asaia Distribution among Different Mosquito Vectors Is Affected by Tissue Localization and Host Species
by Mahdokht Ilbeigi Khamseh Nejad, Alessia Cappelli, Claudia Damiani, Monica Falcinelli, Paolo Luigi Catapano, Ferdinand Nanfack-Minkeu, Marie Paul Audrey Mayi, Chiara Currà, Irene Ricci and Guido Favia
Microorganisms 2024, 12(3), 545; https://doi.org/10.3390/microorganisms12030545 - 08 Mar 2024
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Abstract
Microbial communities play an important role in the fitness of mosquito hosts. However, the factors shaping microbial communities in wild populations, with regard to interactions among microbial species, are still largely unknown. Previous research has demonstrated that two of the most studied mosquito [...] Read more.
Microbial communities play an important role in the fitness of mosquito hosts. However, the factors shaping microbial communities in wild populations, with regard to interactions among microbial species, are still largely unknown. Previous research has demonstrated that two of the most studied mosquito symbionts, the bacteria Wolbachia and Asaia, seem to compete or not compete, depending on the genetic background of the reference mosquito host. The large diversity of WolbachiaAsaia strain combinations that infect natural populations of mosquitoes may offer a relevant opportunity to select suitable phenotypes for the suppression of pathogen transmission and for the manipulation of host reproduction. We surveyed Wolbachia and Asaia in 44 mosquito populations belonging to 11 different species of the genera Anopheles, Aedes, and Culex using qualitative PCR. Through quantitative PCR, the amounts of both bacteria were assessed in different mosquito organs, and through metagenomics, we determined the microbiota compositions in some selected mosquito populations. We show that variation in microbial community structure is likely associated with the species/strain of mosquito, its geographical position, and tissue localization. Together, our results shed light on the interactions among different bacterial species in the microbial communities of mosquito vectors, and this can aid the development and/or improvement of methods for symbiotic control of insect vectors. Full article
(This article belongs to the Special Issue Microbiota of Insect Vectors)
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