Infectious Diseases: New Approaches to Old Problems 3.0

Dear Colleagues,

This Special Issue is the continuation of our previous Special Issue, entitled “Infectious Diseases: New Approaches to Old Problems 2.0”.

After living in a time of widespread concern regarding COVID-19, the threat still remains, with infectious diseases one of the leading causes of death worldwide. Pathogens are responsible for countless outbreaks of disease among humans, with significant impacts on public health as well as the economy. The increase in antibiotic resistance is a well-known phenomenon that has begun to form a new pandemic; nevertheless, the concept of One Health has hallmarked the lack of prevention in control in other areas that have great implications for human health. Also, one trait common to most pathogens is their ability to modulate, manipulate, and escape host immune responses. The scientific community must develop innovative diagnostics that provide sample-to-answer techniques to readily analyze on-site data in the field, as well as new therapeutic alternatives. Therefore, immunomodulation approaches, such as adjuvants, therapies, and vaccines, appear to be the most compelling and promising methods with which to enhance immune responses. Importantly, bacteria, along with viruses and parasites, are great hazards and a challenge to prevent as well as treat.

The aim of this Special Issue is to unite several fields of research to approach the problem from a One Health perspective. The need for this Issue emerges because of the lack of strategies and solutions to overcome infectious diseases in the framework of technology and the interconnected world. It will also be a platform on where novel strategies for vaccine and therapeutic development will be provided, focusing on immunomodulation. 

Dr. Monica Cartelle Gestal
Dr. Eva Torres-Sangiao
Dr. Nelson C. Soares
Guest Editors

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• infectious diseases
• antibiotic resistance
• vaccines and therapies
• biomarkers and diagnosis
• mass spectrometry
• immunomodulation
• inflammation
• systems biology
• metabolomics