Biocompatible Surface Functionalization of Nanomaterials
A special issue of Materials (ISSN 1996-1944).
Deadline for manuscript submissions: closed (15 June 2019) | Viewed by 10046
Interests: innate immune system; chemokines; nanomaterials; nanobiointeractions; adjuvants
Special Issues, Collections and Topics in MDPI journals
Nanomaterials have become a consolidated technology over the last two decades. As we know, many nanotools contain toxic materials or specific dangerous synthesis by-products. On the other hand, they demonstrate important intrinsic features to be exploited in diagnostics (e.g., specific wavelength light emission or absorption) or drug delivery (e.g., pH-responsiveness). Full biocompatibility is needed to prepare successful nano-products for application in the biomedical field. This goal can be obtained by providing specific surface functionalization of the nanomaterials aimed at confining or abrogate their core toxicity. Common techniques of surface coating are currently exploited using biocompatible polymers, organic or biological molecules. These procedures are not always effective in biological environments. Major difficulties are related to the dispersion/aggregation of nanomaterials in colloidal suspensions and the stability of the attached biocompatible moieties.
The present Special Issue is aimed at providing novel approaches to biocompatible nanomaterials’ functionalization. The focus is on the biocompatibility, immune escape or immune-stimulation, and enhanced performances of nanomaterials for biomedical applications. Innovative research articles, as well as critical reviews of the literature, will be welcome to provide an expert opinion and critical discussion.
Dr. Giuseppe Bardi
Manuscript Submission Information
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- biomedical applications
- immune escape
- immune stimulation
- colloidal suspensions