Genetic Insights into Liver Diseases
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Genetics and Genomics".
Deadline for manuscript submissions: 14 June 2024 | Viewed by 149
Special Issue Editors
Interests: genetics; liver; steatosis; disease progression; transcription control; epigenetics
Interests: liver; cirrhosis; disease progression; gastroenterology; disease clinical approach; genetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The role of heritability/genetics in the pathogenesis of liver disease is a fascinating field and is under exploration, particularly with regard to the polymorphisms involved in the management of lipid droplets. Although a number of studies have examined the possible association between the genetics of liver and disease development or progression, the clinical utility of polygenic risk scores (PRS) in the clinical management of patients is still being investigated.
Moreover, determining whether the role of some gene variants can be confirmed in the progression of non-cirrhotic to cirrhosis disease and defining how genetic factors could combine with clinical signs in this disease would be useful support tools for the diagnosis and evaluation of chronic liver disease progression, thus facilitating the development of personalized and targeted therapeutics for patients.
Dr. Monica Mischitelli
Dr. Flaminia Ferri
Guest Editors
Manuscript Submission Information
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Keywords
- liver genetics
- liver disease progression
- personalized medicine
- genetic risk score
