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The Challenges and Prospects in Diagnostics of Otolaryngology
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The Challenges and Prospects in Diagnostics of Otolaryngology

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".

Deadline for manuscript submissions: closed (5 February 2024) | Viewed by 5323

Special Issue Editor

Prof. Dr. Elena Cantone

E-Mail Website
Guest Editor
Department of Neuroscience and Reproductive and Odontostomatological Sciences, “Federico II” University of Naples, AOU Federico II Naples, Naples, Italy
Interests: laryngology; rhinology; biologics; head and neck oncology; chemical sense; neuroimaging; pediatric otorhinolaryngology; head and neck surgery; otorhinolaryngology; personalized medicine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the last decade, precision medicine has revolutionized clinical practice and, in particular, otorhinolaryngology.

Every day we are faced with new diagnostic challenges that require a meticulous and often multidisciplinary diagnostic process.

The purpose of this Special Issue is to offer readers and colleagues several new diagnostic tools in the otorhinolaryngologic fields and beyond.

For instance, with the perspective of precision medicine and a multidisciplinary approach, this Special Issue aims to describe not only the new challenges in otorhinolaryngological diagnostics but also to provide useful tools in clinical practice to personalize therapeutic strategies with a view to patient customization.

Furthermore, the need for an integrated multidisciplinary approach in the evaluation of pathologies in the rhinological, otological, and laryngological fields cannot be overlooked.

These are the reasons why I proposed this Special Issue of the Journal of Personalized Medicine, to collect papers about “The Challenges and Prospects in Diagnostics of Otolaryngology” in all of the fields of otorhinolaryngology as well as in related fields. Studies should describe challenges and prospects in the diagnostics of otorhinolaryngology using basic-science-, clinical-, and population-based approaches.

Prof. Dr. Elena Cantone
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck oncology
  • rhinology
  • otology
  • laryngology
  • lmmunology
  • biomarkers
  • OSAS
  • EGPA
  • diagnosis
  • precision medicine
  • biomarkers
  • diagnostic tools
  • QoL

Published Papers (3 papers)

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Editorial

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4 pages, 202 KiB  
Editorial
A Multidisciplinary Approach for Type 2 Allergic Diseases: What Do Biologics Teach Us?
by Mauro Maniscalco, Aikaterini Detoraki, Giovanni Sarnelli, Maria Nolano, Amato De Paulis, Giuseppe Spadaro and Elena Cantone
J. Pers. Med. 2023, 13(6), 941; https://doi.org/10.3390/jpm13060941 - 1 Jun 2023
Viewed by 1265
Abstract
Patients with atopic/allergic disorders, including atopic dermatitis (AD), allergic rhino-conjunctivitis (AR), chronic rhinosinusitis with/without nasal polyps (CRSwNP/CRSsNP), bronchial asthma, food allergy, and eosinophilic esophagitis (EoE), often share a common genetic background, a type Th2 polarized immune response, and several environmental factors [...] Full article
(This article belongs to the Special Issue The Challenges and Prospects in Diagnostics of Otolaryngology)

Research

Jump to: Editorial

8 pages, 731 KiB  
Article
Treatment Results of Endoscopic Transnasal Orbital Decompression for Graves’ Orbitopathy—A Single-Center Retrospective Analysis in 28 Orbits of 16 Patients
by Krzysztof B. Poślednik, Katarzyna Czerwaty, Nils Ludwig, Marta Molińska-Glura, Anna Jabłońska-Pawlak, Piotr Miśkiewicz, Ireneusz Kantor, Karolina Dżaman, Anna M. Cyran and Mirosław J. Szczepański
J. Pers. Med. 2022, 12(10), 1714; https://doi.org/10.3390/jpm12101714 - 14 Oct 2022
Cited by 2 | Viewed by 1511
Abstract
Graves’ orbitopathy (GO) is an extrathyroidal manifestation of Graves’ disease (GD), which can be associated with corneal ulcerations or optic neuropathy in severe forms. Transnasal endoscopic orbital decompression (TEOD) is a surgical procedure performed in order to decrease the intraorbital pressure by removing [...] Read more.
Graves’ orbitopathy (GO) is an extrathyroidal manifestation of Graves’ disease (GD), which can be associated with corneal ulcerations or optic neuropathy in severe forms. Transnasal endoscopic orbital decompression (TEOD) is a surgical procedure performed in order to decrease the intraorbital pressure by removing part of its bony borders in cases with excessive mass in orbit. The aim of this study was to present the results and evaluate the efficacy of TEOD for GO. The retrospective study included 28 orbits (16 patients) who underwent TEOD from 2017 to 2020. Outcome was evaluated based on visual acuity improvement, clinical activity score (CAS) decrease, proptosis, and intraocular pressure (IOP) reduction. A preoperative best-corrected visual acuity (BCVA) increased from 0.69 ± 0.385 (mean ± standard deviation) to 0.74 ± 0.332 (p = 0.17) postoperatively. CAS decreased in 15 orbits postoperatively. Proptosis decreased from 22.89 ± 1.873 mm to 21.25 ± 2.053 mm (p < 0.05). IOP decreased from a preoperative 16.11 ± 3.93 mmHg to 14.40 ± 3.27 mmHg (p < 0.05) postoperatively. In addition, postoperative relief of exposure keratitis was observed. The analysis of development of iatrogenic diplopia revealed increasing in degree of diplopia. TEOD shows rare complications, but significant improvements in BCVA, CAS, proptosis, and IOP. Full article
(This article belongs to the Special Issue The Challenges and Prospects in Diagnostics of Otolaryngology)
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9 pages, 7517 KiB  
Article
Minimal Margin Surgery and Intraoperative Neuromonitoring in Benign Parotid Gland Tumors: Retrospective Clinical Study
by Eva Aurora Massimilla, Giovanni Motta, Michelangelo Magaldi, Marco Montella, Gaetana Messina, Domenico Testa, Elena Cantone and Gaetano Motta
J. Pers. Med. 2022, 12(10), 1641; https://doi.org/10.3390/jpm12101641 - 3 Oct 2022
Cited by 2 | Viewed by 1629
Abstract
Extracapsular dissection (ECD) was introduced for the removal of superficial and small benign parotid tumors. According to a recent proposal, ECD is reserved for tumors that are 3 cm or less, mobile, and close to the parotid borders in cases of pleomorphic adenoma. [...] Read more.
Extracapsular dissection (ECD) was introduced for the removal of superficial and small benign parotid tumors. According to a recent proposal, ECD is reserved for tumors that are 3 cm or less, mobile, and close to the parotid borders in cases of pleomorphic adenoma. The aim of the study is to evaluate the effectiveness of ECD for treatment of benign parotid tumors also in cases of tumors that were larger than 3 cm and deeper. All ECD for benign parotid neoplasms conducted between 2007 and 2017 were reviewed. The lesions included were limited to primary parotid tumors and categorized by Quer proposal. Facial nerve monitoring was used in all cases. Facial nerve palsy and local recurrences were assessed. The 88 ECD performed met inclusion criteria. The mean lesion size was 4.26 cm. Of the tumors, 68 were less than 3 cm in diameter and 20 were larger, 64 were superficial, and 24 were deep. The most common lesion types were pleomorphic adenoma (88.6%). There was no significant difference in complication rates between the size of tumor (p = 0.9) and location (p = 0.91). Our results suggest that extracapsular dissection could be considered an option for first-time diagnosed benign parotid tumors, even in cases of large dimensions and deep lobe involvement. Full article
(This article belongs to the Special Issue The Challenges and Prospects in Diagnostics of Otolaryngology)
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