Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.0
4.8
Journals
JFB
Special Issues
Hydrogels for Biointerface Application
share announcement

Hydrogels for Biointerface Application

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials for Drug Delivery".

Deadline for manuscript submissions: closed (20 February 2024) | Viewed by 8150

Special Issue Editors

Prof. Dr. Fanfan Fu

E-Mail Website
Guest Editor
School of Environment and Biological Engineering, Nanjing University of Science and Technology, Nanjing, China
Interests: smart hydrogels; hydrogel biointerface; biosensor; biomedical device; organ on chips
Dr. Benqing Zhou

E-Mail Website
Guest Editor
Department of Biomedical Engineering, Shantou University, Shantou, China
Interests: nanomedicine; biomaterials; cancer therapy; cancer imaging; photoimmunotherapy
Dr. Ze Zhao

E-Mail Website
Guest Editor
School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore
Interests: colloidal crystal; biomaterials; bio-inspired materials; responsive materials; tissue engineering

Special Issue Information

Dear Colleagues,

Functional and smart hydrogels are widely used for biointerfaces, such as artificial skin, flexible and implantable bioelectronics, and tissue engineering. The essential attribute of the hydrogel is polymer networks with a high-water content that allows for the transport of biological and chemical molecules, thus providing an extracellular matrix-like (ECM-like) environment to facilitate the exchange of biological molecular and markers across interfaces.

In this Special Issue, we intend to provide detailed and in-depth exploration and discussion in designing hydrogels for biointerface application. The interests of this topic include, but are not limited to, the novel components, strategies, high performance (e.g., toughness, stretchability, and biocompatibility), and features (e.g., self-healing, shape memory, and wet adhesion, conductive hydrogels) of the hydrogel, and the fundamental study of the hydrogels for biointerface.

We hope that this Special Issue can bring new knowledge and ideas for all the related fields. Original research articles and concise and precise reviews are both accepted.

Prof. Dr. Fanfan Fu
Dr. Benqing Zhou
Dr. Ze Zhao
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hydrogels
  • biointerface
  • functional polymers
  • smart materials
  • biosensor

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

12 pages, 2524 KiB  
Article
Antitumor Efficacy of Doxorubicin-Loaded Electrospun Attapulgite–Poly(lactic-co-glycolic acid) Composite Nanofibers
by Zhe Wang, Yili Zhao, Mingwu Shen, Helena Tomás, Benqing Zhou and Xiangyang Shi
J. Funct. Biomater. 2022, 13(2), 55; https://doi.org/10.3390/jfb13020055 - 10 May 2022
Cited by 8 | Viewed by 3827
Abstract
Currently, cancer chemotherapeutic drugs still have the defects of high toxicity and low bioavailability, so it is critical to design novel drug release systems for cancer chemotherapy. Here, we report a method to fabricate electrospun drug-loaded organic/inorganic hybrid nanofibrous system for antitumor therapy [...] Read more.
Currently, cancer chemotherapeutic drugs still have the defects of high toxicity and low bioavailability, so it is critical to design novel drug release systems for cancer chemotherapy. Here, we report a method to fabricate electrospun drug-loaded organic/inorganic hybrid nanofibrous system for antitumor therapy applications. In this work, rod-like attapulgite (ATT) was utilized to load a model anticancer drug doxorubicin (DOX), and mixed with poly(lactic-co-glycolic acid) (PLGA) to form electrospun hybrid nanofibers. The ATT/DOX/PLGA composite nanofibers were characterized through various techniques. It is feasible to load DOX onto ATT surfaces, and the ATT/DOX/PLGA nanofibers show a smooth and uniform morphology with improved mechanical durability. Under neutral and acidic pH conditions, the loaded DOX was released from ATT/DOX/PLGA nanofibers in a sustained manner. In addition, the released DOX from the nanofibers could significantly inhibit the growth of tumor cells. Owing to the significantly reduced burst release profile and increased mechanical durability of the ATT/DOX/PLGA nanofibers, the designed organic–inorganic hybrid nanofibers may hold great promise as a nanoplatform to encapsulate different drugs for enhanced local tumor therapy applications. Full article
(This article belongs to the Special Issue Hydrogels for Biointerface Application)
►▼ Show Figures

Figure 1

Review

Jump to: Research

27 pages, 4268 KiB  
Review
Polyethyleneimine-Based Drug Delivery Systems for Cancer Theranostics
by Chong Zhao and Benqing Zhou
J. Funct. Biomater. 2023, 14(1), 12; https://doi.org/10.3390/jfb14010012 - 23 Dec 2022
Cited by 13 | Viewed by 3744
Abstract
With the development of nanotechnology, various types of polymer-based drug delivery systems have been designed for biomedical applications. Polymer-based drug delivery systems with desirable biocompatibility can be efficiently delivered to tumor sites with passive or targeted effects and combined with other therapeutic and [...] Read more.
With the development of nanotechnology, various types of polymer-based drug delivery systems have been designed for biomedical applications. Polymer-based drug delivery systems with desirable biocompatibility can be efficiently delivered to tumor sites with passive or targeted effects and combined with other therapeutic and imaging agents for cancer theranostics. As an effective vehicle for drug and gene delivery, polyethyleneimine (PEI) has been extensively studied due to its rich surface amines and excellent water solubility. In this work, we summarize the surface modifications of PEI to enhance biocompatibility and functionalization. Additionally, the synthesis of PEI-based nanoparticles is discussed. We further review the applications of PEI-based drug delivery systems in cancer treatment, cancer imaging, and cancer theranostics. Finally, we thoroughly consider the outlook and challenges relating to PEI-based drug delivery systems. Full article
(This article belongs to the Special Issue Hydrogels for Biointerface Application)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop