Innovative Biomaterials for Tissue Engineering: Regeneration of Soft and Hard Tissues—Volume II

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials for Tissue Engineering and Regenerative Medicine".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 3142

Special Issue Editors


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Guest Editor
1. Dipartimento Scienze della Vita e Sanità Pubblica, Università Cattolica del Sacro Cuore, 00168 Rome, Italy
2. Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy
Interests: bone biology; osteogenic mechanisms; bone regenerative strategies; orthopedics; craniofacial surgery
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Special Issue Information

Dear Colleagues,

The wide complexity and heterogeneity of human tissues justify the emergence in the 1980s of tissue engineering as a biomedical science area, which underwent exponential growth thereafter. Tissue engineering aims to regenerate human tissues and organs (e.g., bone, cartilage, skin, and liver), bridging structure with function as a paramount challenge. Due to its cross-domain nature, tissue engineering (TE) gathers scientists, engineers, and physicians in multidisciplinary teams using a variety of methods to construct biological substitutes. Most human native tissues are made of complex three-dimensional (3D) structures, presenting different shapes, architectures, and extracellular matrix compositions. Several efforts have been made, by research groups spread worldwide, to develop constructs that can mimic the complexity of native tissues; however, the achievement of 3D complex organ structures is far from being tangible. Furthermore, these tissues, which are not static, have unique functions suited to dynamic changes in tissue conformations. For this Special Issue, we will include original articles presenting the latest developments in biomaterials and TE strategies for the development of biologically functional products with structural organization. In addition, updated review manuscripts able to stimulate creative thinking will be highlighted.

Dr. Pedro Morouço
Dr. Wanda Lattanzi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • scaffolds
  • bioprinting
  • regenerative medicine
  • cells
  • mesenchymal stromal cells
  • nanotechnologies
  • nanomaterials

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Published Papers (2 papers)

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Review

29 pages, 4486 KiB  
Review
Zinc Oxide-Based Nanomaterials for Microbiostatic Activities: A Review
by Alemtsehay Tesfay Reda, Jae Yeon Park and Yong Tae Park
J. Funct. Biomater. 2024, 15(4), 103; https://doi.org/10.3390/jfb15040103 - 15 Apr 2024
Viewed by 699
Abstract
The world is fighting infectious diseases. Therefore, effective antimicrobials are required to prevent the spread of microbes and protect human health. Zinc oxide (ZnO) nano-materials are known for their antimicrobial activities. Because of their distinctive physical and chemical characteristics, they can be used [...] Read more.
The world is fighting infectious diseases. Therefore, effective antimicrobials are required to prevent the spread of microbes and protect human health. Zinc oxide (ZnO) nano-materials are known for their antimicrobial activities. Because of their distinctive physical and chemical characteristics, they can be used in medical and environmental applications. ZnO-based composites are among the leading sources of antimicrobial research. They are effective at killing (microbicidal) and inhibiting the growth (microbiostatic) of numerous microorganisms, such as bacteria, viruses, and fungi. Although most studies have focused on the microbicidal features, there is a lack of reviews on their microbiostatic effects. This review provides a detailed overview of available reports on the microbiostatic activities of ZnO-based nano-materials against different microorganisms. Additionally, the factors that affect the efficacy of these materials, their time course, and a comparison of the available antimicrobials are highlighted in this review. The basic properties of ZnO, challenges of working with microorganisms, and working mechanisms of microbiostatic activities are also examined. This review underscores the importance of further research to better understand ZnO-based nano-materials for controlling microbial growth. Full article
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21 pages, 1643 KiB  
Review
Peptide-Based Hydrogels: Template Materials for Tissue Engineering
by Roya Binaymotlagh, Laura Chronopoulou and Cleofe Palocci
J. Funct. Biomater. 2023, 14(4), 233; https://doi.org/10.3390/jfb14040233 - 19 Apr 2023
Cited by 5 | Viewed by 1918
Abstract
Tissue and organ regeneration are challenging issues, yet they represent the frontier of current research in the biomedical field. Currently, a major problem is the lack of ideal scaffold materials’ definition. As well known, peptide hydrogels have attracted increasing attention in recent years [...] Read more.
Tissue and organ regeneration are challenging issues, yet they represent the frontier of current research in the biomedical field. Currently, a major problem is the lack of ideal scaffold materials’ definition. As well known, peptide hydrogels have attracted increasing attention in recent years thanks to significant properties such as biocompatibility, biodegradability, good mechanical stability, and tissue-like elasticity. Such properties make them excellent candidates for 3D scaffold materials. In this review, the first aim is to describe the main features of a peptide hydrogel in order to be considered as a 3D scaffold, focusing in particular on mechanical properties, as well as on biodegradability and bioactivity. Then, some recent applications of peptide hydrogels in tissue engineering, including soft and hard tissues, will be discussed to analyze the most relevant research trends in this field. Full article
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