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New Insights into the Prevention, Diagnosis and Management of Acute...
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New Insights into the Prevention, Diagnosis and Management of Acute Myocardial Infarction

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 1 June 2024 | Viewed by 1410

Special Issue Editors

Dr. Miruna Mihaela Micheu

E-Mail Website
Guest Editor
Department of Cardiology, Clinical Emergency Hospital of Bucharest, Floreasca Street 8, 014461 Bucharest, Romania
Interests: ischemic heart disease; cardiogenetics; biomarkers; advance cardiac imaging
Dr. Alexandru Scafa-Udriste

E-Mail Website
Guest Editor
1. Department of Cardiology, Clinical Emergency Hospital of Bucharest, Floreasca Street 8, 014461 Bucharest, Romania
2. The Board Room, University of Medicine and Pharmacy Carol Davila, Eroii Sanitari Bvd. 8, 050474 Bucharest, Romania
Interests: ischemic heart disease; atherosclerosis; artificial intelligence; advanced coronary imaging

Special Issue Information

Dear Colleagues,

The paradigm surrounding acute myocardial infarction (AMI) has markedly evolved over the last century. Initially diagnosed postmortem and deemed invariably fatal, it has transformed into a condition where survival is now the prevailing norm. AMI is defined as cardiomyocyte necrosis in the clinical setting of acute myocardial ischaemia, most frequently caused by atherothrombotic events. Diagnosis workup entails integration of clinical findings, ECG changes, circulating biomarkers, invasive and non-invasive imaging data, and occasionally pathological findings. Despite diagnostic and therapeutic advancements, AMI remains a leading cause of morbidity and mortality worldwide. Thus, there is a perpetual quest for the development of more refined diagnosis, risk stratification and prediction tools, aimed at enabling a more precise management for patients with AMI.

In this Special Issue, we endeavor to highlight the most recent discoveries pertaining to AMI, encompassing, but not confined to, cutting-edge technological advancements, experimental and clinical studies on disease pathogenesis, timely diagnosis, prognosis, and innovative treatment strategies. Both original research and review papers are welcome.

Dr. Miruna Mihaela Micheu
Dr. Alexandru Scafa-Udriste
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ischemic heart disease
  • myocardial infarction
  • coronary disease
  • atherosclerosis
  • coronary imaging

Published Papers (2 papers)

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Research

7 pages, 208 KiB  
Article
Incidence of Ventricular Fibrillation and Sustained Ventricular Tachycardia Complicating Non-ST Segment Elevation Myocardial Infarction
by Asher Schnur, Moshe Rav Acha, Ranel Loutati, Nimrod Perel, Louay Taha, Netanel Zacks, Tomer Maller, Mohammad Karmi, Feras Bayya, Nir Levi, Pierre Sabouret, Noam Fink, David Marmor, Mony Shuvy, Michael Glikson and Elad Asher
J. Clin. Med. 2024, 13(8), 2286; https://doi.org/10.3390/jcm13082286 - 15 Apr 2024
Viewed by 430
Abstract
Background: Primary ventricular fibrillation (VF) and sustained ventricular tachycardia (VT) are potentially lethal complications in patients suffering from acute myocardial infarction (MI). In contrast with the profound data regarding the incidence and prognostic value of ventricular arrhythmias in ST elevation myocardial infarction (STEMI) [...] Read more.
Background: Primary ventricular fibrillation (VF) and sustained ventricular tachycardia (VT) are potentially lethal complications in patients suffering from acute myocardial infarction (MI). In contrast with the profound data regarding the incidence and prognostic value of ventricular arrhythmias in ST elevation myocardial infarction (STEMI) patients, data regarding contemporary non-ST elevation myocardial infarction (NSTEMI) patients with ventricular arrhythmias is scarce. The aim of the current study was to investigate the incidence of VF/VT complicating NSTEMI among patients admitted to an intensive coronary care unit (ICCU). Methods: Prospective, single-center study of patients diagnosed with NSTEMI admitted to ICCU between June 2019 and December 2022. Data including demographics, presenting symptoms, comorbid conditions, and physical examination, as well as laboratory and imaging data, were analyzed. Patients were continuously monitored for arrhythmias during their admission. The study endpoint was the development of VF/sustained VT during admission. Results: A total of 732 patients were admitted to ICCU with a diagnosis of NSTEMI. Of them, six (0.8%) patients developed VF/VT during their admission. Nevertheless, three were excluded after they were misdiagnosed with NSTEMI instead of posterior ST elevation myocardial infarction (STEMI). Hence, only three (0.4%) NSTEMI patients had VF/VT during admission. None of the patients died during 1-year follow-up. Conclusions: VF/VT in NSTEMI patients treated according to contemporary guidelines including early invasive strategy is rare, suggesting these patients may not need routine monitoring and ICCU setup. Full article
(This article belongs to the Special Issue New Insights into the Prevention, Diagnosis and Management of Acute Myocardial Infarction)
10 pages, 1062 KiB  
Article
The Effect of War on STEMI Incidence: Insights from Intensive Cardiovascular Care Unit Admissions
by Ranel Loutati, Sharon Bruoha, Louay Taha, Mohammad Karmi, Nimrod Perel, Tomer Maller, Itshak Amsalem, Rafael Hitter, Nir Levi, Netanel Zacks, Maayan Shrem, Motaz Amro, Mony Shuvy, Michael Glikson and Elad Asher
J. Clin. Med. 2024, 13(5), 1356; https://doi.org/10.3390/jcm13051356 - 27 Feb 2024
Viewed by 749
Abstract
(1) Background: The impact of armed conflicts on public health is undeniable, with psychological stress emerging as a significant risk factor for cardiovascular disease (CVD). Nevertheless, contemporary data regarding the influence of war on CVD, and especially on acute coronary syndrome (ACS), [...] Read more.
(1) Background: The impact of armed conflicts on public health is undeniable, with psychological stress emerging as a significant risk factor for cardiovascular disease (CVD). Nevertheless, contemporary data regarding the influence of war on CVD, and especially on acute coronary syndrome (ACS), are scarce. Hence, the aim of the current study was to assess the repercussions of war on the admission and prognosis of patients admitted to a tertiary care center intensive cardiovascular care unit (ICCU). (2) Methods: All patients admitted to the ICCU during the first three months of the Israel–Hamas war (2023) were included and compared with all patients admitted during the same period in 2022. The primary outcome was in-hospital mortality. (3) Results: A total of 556 patients (184 females [33.1%]) with a median age of 70 (IQR 59–80) were included. Of them, 295 (53%) were admitted to the ICCU during the first three months of the war. Fewer Arab patients and more patients with ST-segment elevation myocardial infraction (STEMI) were admitted during the war period (21.8% vs. 13.2%, p < 0.001, and 31.9% vs. 24.1%, p = 0.04, respectively), whereas non-STEMI (NSTEMI) patients were admitted more frequently in the pre-war year (19.3% vs. 25.7%, p = 0.09). In-hospital mortality was similar in both groups (4.4% vs. 3.4%, p = 0.71; HR 1.42; 95% CI 0.6–3.32, p = 0.4). (4) Conclusions: During the first three months of the war, fewer Arab patients and more STEMI patients were admitted to the ICCU. Nevertheless, in-hospital mortality was similar in both groups. Full article
(This article belongs to the Special Issue New Insights into the Prevention, Diagnosis and Management of Acute Myocardial Infarction)
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