Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.4
3.9
Journals
JCM
Special Issues
Advances in Diabetic Foot, Its Complications and Related Diseases
share announcement

Advances in Diabetic Foot, Its Complications and Related Diseases

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Endocrinology & Metabolism".

Deadline for manuscript submissions: closed (25 January 2024) | Viewed by 4218

Special Issue Editors

Prof. Dr. Giuseppe Seghieri

E-Mail Website
Guest Editor
Faculty of Physiatry, Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla, 3 - 50134 Florence, Italy
Interests: diabetes; epidemiology and statistics; diabetic foot; vascular complications; pathophysiology of diabetic complications; gender medicine, pregnancy and diabetes
Prof. Dr. Flavia Franconi

E-Mail Website
Guest Editor
Laboratory of Sex-Gender Medicine, National Institute of Biostructures and Biosystems, Sassari, Italy
Interests: sex; gender; cardiovascular drugs; metabolomics
Special Issues, Collections and Topics in MDPI journals
Dr. Matteo Monami

E-Mail Website
Guest Editor
Diabetology, Careggi Hospital and University of Florence, Florence, Italy
Interests: diabetic foot ulcer; diabetic foot care and diabetes complications; cardiovascular disease

Special Issue Information

Dear Colleagues,

Diabetic foot (DF) is a leading cause of disability and early mortality in people with diabetes, with enormous direct and indirect costs for both patients and health systems. It also represents a paradigmatic example of how the collaboration between clinical and basic researchers together with multidisciplinary health professionals can represent an added value for the improvement in all health goals in people with DF, even overcoming the recent (and unfortunately ongoing) storm of the COVID-19 pandemic. Furthermore, this complication appears to affect males far more than females, while little is known about gender differences in the risk of adverse outcomes in people with DF. Consequently, original contributions on this new theme are welcomed, justifying the presence of a Co-Guest Editor with renowned expertise about this aspect (Prof. Franconi).

In conclusion, the purpose of this Special Issue is to provide a comprehensive overview of the up-to-date clinical aspects of DF disease, including the use of innovative techniques and technologies in interventional therapies. For this reason, we encourage multidisciplinary researchers in the field of DF and related diseases to submit their findings as original articles or reviews to this Special Issue.

Prof. Dr. Giuseppe Seghieri
Prof. Dr. Flavia Franconi
Dr. Matteo Monami
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • clinical aspects of diabetic foot
  • novel therapies in diabetic foot
  • vascular complications of diabetes
  • epidemiology
  • gender differences
  • adverse outcomes and cardiovascular complications in diabetic foot

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

33 pages, 19680 KiB  
Article
Patients’ Buying Behavior for Non-Reimbursed Off-Loading Devices Used in Diabetic Foot Ulcer Treatment—An Observational Study during COVID-19 Pandemic from a Romanian Physical Therapy Unit
by Iulia Iovanca Dragoi, Florina Georgeta Popescu, Frank L. Bowling, Cosmina Ioana Bondor and Mihai Ionac
J. Clin. Med. 2023, 12(20), 6516; https://doi.org/10.3390/jcm12206516 - 14 Oct 2023
Viewed by 1300
Abstract
Diabetic foot ulcer non-reimbursed treatment depends on multiple factors, including the patient’s buying behaviors. Factors affecting buying behaviors for the removable off-loading devices are not completely understood. The aim of this study was to investigate the patients’ buying behaviors of the removable off-loading [...] Read more.
Diabetic foot ulcer non-reimbursed treatment depends on multiple factors, including the patient’s buying behaviors. Factors affecting buying behaviors for the removable off-loading devices are not completely understood. The aim of this study was to investigate the patients’ buying behaviors of the removable off-loading devices and their influence on the DFU treatment outcomes remotely monitored during the COVID-19 pandemic. In this prospective observational study, 45 patients affected by diabetic peripheral neuropathy, with/without peripheral arterial disease, with foot ulcers treated with removable devices were remotely monitored. Prefabricated removable cast walkers, insoles, and therapeutic footwear were the proposed off-loading methods. Patients affected by high blood pressure (p = 0.018), peripheral arterial disease (p = 0.029), past amputations (p = 0.018), and ulcer on the left foot (p = 0.007) bought removable cast walkers. Rural provenience (p = 0.011) and male (p = 0.034) did not buy a removable walker. The healing rate was 69.4%, while the median healing time was 20 weeks. High blood pressure negatively influenced healing time (p = 0.020). Patients who bought the most efficient treatment method for DFUs were females from urban provenience, with amputation in the past, with peripheral arterial disease, and with high blood pressure. Full article
(This article belongs to the Special Issue Advances in Diabetic Foot, Its Complications and Related Diseases)
►▼ Show Figures

Graphical abstract

9 pages, 920 KiB  
Article
Impact of Diabetic Foot Multidisciplinary Unit on Incidence of Lower-Extremity Amputations by Diabetic Foot
by Ángel Ortiz-Zúñiga, Jordi Samaniego, Betina Biagetti, Nicolás Allegue, Anna Gené, Andrea Sallent, Almudena Crespo, Jordi Serracanta, Carme Torrents, Daniela Issa, Danilo Rivas, Maria Teresa Veintemillas, Núria Fernández-Hidalgo, Rosa Busquets, Josep Royo and Cristina Hernández
J. Clin. Med. 2023, 12(17), 5608; https://doi.org/10.3390/jcm12175608 - 28 Aug 2023
Cited by 1 | Viewed by 1153
Abstract
Background: One of the most devastating complications of diabetes is diabetes-related foot disease (DFD), which is a priority for public health systems. The 2016–2020 Catalonia Health Plan aimed to reduce the incidence of total and major lower-extremity amputations (LEAs) due to DFD by [...] Read more.
Background: One of the most devastating complications of diabetes is diabetes-related foot disease (DFD), which is a priority for public health systems. The 2016–2020 Catalonia Health Plan aimed to reduce the incidence of total and major lower-extremity amputations (LEAs) due to DFD by 10% in the population aged 45–74 years. The aim of the present study was to compare the incidence of LEA-DFD 5 years before and after the creation of the Diabetic Foot Multidisciplinary Unit at our Hospital. Methods: We prospectively collected all cases of LEA-DFD performed at Vall d’Hebron University Hospital from 1 January 2016 to 31 December 2020. Cases of LEA-DFD performed from 1 January 2011 to 31 December 2015 were retrospectively reviewed. The incidence of LEA-DFD between these periods was compared. Results: A total of 457 LEAs due to DFD were performed in 316 patients. We observed a reduction of 27.9% [CI: 23.7–32.1%] in the incidence of total LEA in the 2016–2020 period in comparison with the period 2011–2016 (0.8 ± 0.1 vs. 1.1 ± 0.3 per 10.000 inhabitants/year, p < 0.001), as well as a reduction of 49.3% [CI: 44.6–53.9%] in the incidence of major LEA-DFD (0.15 ± 0.1 vs. 0.30 ± 0.1 per 10.000 inhabitants/year, p < 0.001). Conclusions: The implementation of a Diabetic Foot Multidisciplinary Unit resulted in a significant reduction in the rate of amputations due to DFD in the population with diabetes in North Barcelona. Full article
(This article belongs to the Special Issue Advances in Diabetic Foot, Its Complications and Related Diseases)
►▼ Show Figures

Figure 1

9 pages, 1235 KiB  
Article
Metrics of Gender Differences in Mortality Risk after Diabetic Foot Disease
by Giuseppe Seghieri, Elisa Gualdani, Piergiorgio Francia, Ilaria Campesi, Flavia Franconi, Graziano Di Cianni and Paolo Francesconi
J. Clin. Med. 2023, 12(9), 3288; https://doi.org/10.3390/jcm12093288 - 5 May 2023
Cited by 1 | Viewed by 1037
Abstract
Background: The aim of this study was to clarify any gender differences in the mortality risk of people with DFD since patients with diabetic foot disease (DFD) are at a high risk of mortality and, at the same time, are more likely to [...] Read more.
Background: The aim of this study was to clarify any gender differences in the mortality risk of people with DFD since patients with diabetic foot disease (DFD) are at a high risk of mortality and, at the same time, are more likely to be men. Methods: From regional administrative sources, the survival probability was retrospectively evaluated by the Kaplan-Meier method and using the Cox proportional-hazards model comparing people with DFD to those without DFD across the years 2011–2018 in Tuscany, Italy. Gender difference in mortality was evaluated by the ratio of hazard ratios (RHR) of men to women after initial DFD hospitalizations (n = 11,529) or in a cohort with prior history of DFD hospitalizations (n = 11,246). Results: In both cohorts, the survival probability after DFD was lower among women. Compared to those without DFD, after initial DFD hospitalizations, the mortality risk was significantly (18%) higher for men compared to women. This excess risk was particularly high after major amputations but also after ulcers, infections, gangrene, or Charcot, with a lower reduction after revascularization procedures among men. In the cohort that included people with a history of prior DFD hospitalizations, except for the risk of minor amputations being higher for men, there was no gender difference in mortality risk. Conclusions: In people with DFD, the overall survival probability was lower among women. Compared to those without DFD after a first DFD hospitalization, men were at higher risk of mortality. This excess risk disappeared in groups with a history of previous DFD hospitalizations containing a greater percentage of women who were older and probably had a longer duration of diabetes and thus becoming, over time, progressively frailer than men. Full article
(This article belongs to the Special Issue Advances in Diabetic Foot, Its Complications and Related Diseases)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop