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Recent Advances in Dental Implantology: Part II
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Recent Advances in Dental Implantology: Part II

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: closed (2 December 2023) | Viewed by 5895

Special Issue Editor

Prof. Dr. Daniele De Santis

E-Mail Website
Guest Editor
Head and Neck Department, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37124 Verona, Italy
Interests: digital flow in dental surgery; computerized dentistry; tissue engineering; oral and facial pain; genetics; quality of life; dental implantology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is with great pleasure and satisfaction that I communicate to you the upcoming Boutique Special Issue: "Recent Advances in Dental Implantology: Part II", following the great editorial success of the first edition. Certainly, these challenges continue to fascinate us, and in this regard I would like to invite you to contribute to a second editorial project focused on a range of inter- and multidisciplinary topics aligned with the same common denominators: bone tissue, metabolism and histomorphometric determinants depending on impacting factors.

We all know that the main objective of our daily clinical practice is to improve quality of life.

As the Guest Editor of this Boutique Special Issue, it is my intention to gather the current research related to these topics, and work with some of the leading global experts in the field of dentistry.

Furthermore, there is the possibility that MDPI may consider publishing the articles featured in this Special Issue in a book.

Prof. Dr. Daniele De Santis
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dentistry
  • dental Implantology
  • dental Implants
  • digital flow in dental surgery
  • computerized dentistry
  • digital dentistry
  • tissue engineering

Published Papers (4 papers)

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Research

10 pages, 1034 KiB  
Article
Anti-CGRP and Anti-CGRP Receptor Monoclonal Antibodies for Migraine Prophylaxis: Retrospective Observational Study on 209 Patients
by Vittorio Schweiger, Paola Bellamoli, Francesco Taus, Leonardo Gottin, Alvise Martini, Marta Nizzero, Eleonora Bonora, Giovanna Del Balzo, Katia Donadello, Erica Secchettin, Gabriele Finco, Daniele De Santis and Enrico Polati
J. Clin. Med. 2024, 13(4), 1130; https://doi.org/10.3390/jcm13041130 - 17 Feb 2024
Viewed by 669
Abstract
Background: Migraine is a neurological disorder characterized by attacks of head pain with prevalent unilateral localization, moderate to high intensity and specifically associated accompanying symptoms. Methods: In this retrospective observational study, we analyzed data regarding 209 patients who had previously been diagnosed with [...] Read more.
Background: Migraine is a neurological disorder characterized by attacks of head pain with prevalent unilateral localization, moderate to high intensity and specifically associated accompanying symptoms. Methods: In this retrospective observational study, we analyzed data regarding 209 patients who had previously been diagnosed with migraine and who were prescribed, between 2019 and 2022, subcutaneous injections of anti-CGRP monoclonal antibodies (mAbs) fremanezumab or galcanezumab or anti-CGRP receptors mAb erenumab regardless of the concomitant assumption of any other acute-phase or prophylactic migraine medication. Results: Regarding efficacy, in the 205 analyzed patients, the change from baseline in terms of MIDAS, HIT-6, MMDs and MAD scores was statistically significant for erenumab and galcanezumab, while for fremanezumab a statistical significance was not achieved likely due to the small sample size. In the treated population, 36 patients (17.5%) reported AEs (pain during injection, transient injection site erythema, nausea, constipation and fatigue). Only 5 patients (2.4%) discontinued the treatment for AEs while 15 patients (7.3%) left for lack of efficacy. Conclusions: this retrospective study comes out in favor of both significant efficacy and safety of anti-CGRP and anti-CGRP receptors mAbs in migraine patients. Further methodologically stronger studies are necessary to validate our observation. Full article
(This article belongs to the Special Issue Recent Advances in Dental Implantology: Part II)
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14 pages, 2418 KiB  
Article
Investigation of the Influence of Roughness and Dental Implant Design on Primary Stability via Analysis of Insertion Torque and Implant Stability Quotient: An In Vitro Study
by Marta Romero, Mariano Herrero-Climent, Blanca Ríos-Carrasco, Aritza Brizuela, Manuel María Romero and Javier Gil
J. Clin. Med. 2023, 12(13), 4190; https://doi.org/10.3390/jcm12134190 - 21 Jun 2023
Cited by 2 | Viewed by 1052
Abstract
In the placement of dental implants, the primary fixation between the dental implant and the bone is of great importance and corresponds to compressive mechanical fixation that aims to prevent micromovement of the implant. The aim of this research was to determine the [...] Read more.
In the placement of dental implants, the primary fixation between the dental implant and the bone is of great importance and corresponds to compressive mechanical fixation that aims to prevent micromovement of the implant. The aim of this research was to determine the role of roughness and the type of dental implant (tissue-level or bone-level) in implant stability, measured using resonance frequency analysis (RFA) and insertion torque (IT). We analyzed 234 titanium dental implants, placed in fresh calf ribs, at the half-tissue level and half-bone level. The implant surface was subjected to grit-blasting treatments with alumina particles of 120, 300, and 600 μm at a projection pressure of 2.5 bar, resulting in three types of roughness. Roughness was determined via optical interferometry. The wettability of the surfaces was also determined. Implant stability was measured using a high-precision torquemeter to obtain IT, and RFA was used to determine the implant stability quotient (ISQ). The results show that rough surfaces with Sa values of 0.5 to 4 μm do not affect the primary stability. However, the type of implant is important; bone-level implants obtained the highest primary stability values. A good correlation between the primary stability values obtained via IT and ISQ was demonstrated. New in vivo studies are necessary to know whether these results can be maintained in the long term. Full article
(This article belongs to the Special Issue Recent Advances in Dental Implantology: Part II)
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11 pages, 6269 KiB  
Article
Mandibular Flexure and Its Significance: An In Vivo Cone Beam-Computed Tomography Proof-of-Concept Study
by Jimmy Londono, Todd R. Schoenbaum, Alma Veronica Varilla Ortiz, Guillermo Franco-Romero, Vanessa Villalobos, Paolo Carosi, Eitan Mijiritsky and Alessandro Pozzi
J. Clin. Med. 2023, 12(12), 4149; https://doi.org/10.3390/jcm12124149 - 20 Jun 2023
Viewed by 1045
Abstract
The aim of this study was to assess intra-arch mandibular dimensional changes that may occur during mouth opening using cone beam-computed tomography (CBCT). Fifteen patients in need of any type of treatment whose execution considered a pre- and post-CBCT assessment consented and were [...] Read more.
The aim of this study was to assess intra-arch mandibular dimensional changes that may occur during mouth opening using cone beam-computed tomography (CBCT). Fifteen patients in need of any type of treatment whose execution considered a pre- and post-CBCT assessment consented and were enrolled. CBCTs were taken with the following settings: 90 kV, 8 mA, field of view (FOV) 140 by 100 mm (height and diameter), Voxel size 0.25 mm (high resolution). The pre-CBCT was executed in the maximum mandibular opening (MO), while the post-CBCT was in the maximum intercuspation (MI). A thermoplastic stent with radiopaque fiducial markers (steel ball bearings) was fabricated for each patient. Measurements were made using radiographic markers between contralateral canines and contralateral first molars and between ipsilateral canines and first molars on both sides. Paired t-tests were performed to evaluate the difference between open and closed positions on these four measurements. In the MO position were registered a significative tightening of the mandible at the canine (−0.49 mm, SD 0.54 mm; p < 0.001) and molar points (−0.81 mm, SD 0.63 mm; p < 0.001) and a significative shortening of the mandible on the right (−0.84 mm, SD 0.80 mm; p < 0.001) and left sides (−0.87 mm, SD 0.49 mm; p < 0.001). Within the study limitations, mandibular flexure determined a significant shortening and tightening between maximum intercuspation to maximum opening positions. Mandibular dimensional changes should be considered in light of other patient factors in the treatment planning of implant positioning and long-span complete arch implant-supported fixed prostheses in order to avoid technical complications. Full article
(This article belongs to the Special Issue Recent Advances in Dental Implantology: Part II)
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10 pages, 2118 KiB  
Article
Dental Implant Surface Decontamination and Surface Change of an Electrolytic Method versus Mechanical Approaches: A Pilot In Vitro Study
by Mariana Anselmo Assunção, João Botelho, Vanessa Machado, Luís Proença, António P. A. Matos, José João Mendes, Lucinda J. Bessa, Nuno Taveira and Alexandre Santos
J. Clin. Med. 2023, 12(4), 1703; https://doi.org/10.3390/jcm12041703 - 20 Feb 2023
Cited by 1 | Viewed by 2425
Abstract
Dental implants are the preferred fixed oral rehabilitation for replacing lost teeth. When peri-implant tissues become inflamed, the removal of plaque accumulating around the implant becomes imperative. Recently, several new strategies have been developed for this purpose, with electrolytic decontamination showing increased potential [...] Read more.
Dental implants are the preferred fixed oral rehabilitation for replacing lost teeth. When peri-implant tissues become inflamed, the removal of plaque accumulating around the implant becomes imperative. Recently, several new strategies have been developed for this purpose, with electrolytic decontamination showing increased potential compared to traditional mechanical strategies. In this in vitro pilot study, we compare the efficacy of an electrolytic decontaminant (Galvosurge®) with an erythritol jet system (PerioFlow®) and two titanium brushes (R-Brush™ and i-Brush™) in removing Pseudomonas aeruginosa PAO1 biofilms from implants. Changes in the implant surface after each approach were also evaluated. Twenty titanium SLA implants were inoculated with P. aeruginosa and then randomly assigned to each treatment group. After treatment, decontamination efficacy was assessed by quantifying colony-forming units (log10 CFU/cm2) from each implant surface. Scanning electron microscopy was used to analyse changes in the implant surface. With the exception of R-Brush, all treatment strategies were similarly effective in removing P. aeruginosa from implants. Major surface changes were observed only in implants treated with titanium brushes. In conclusion, this pilot study suggests that electrolytic decontamination, erythritol-chlorhexidine particle jet system and i-Brush™ brushing have similar performance in removing P. aeruginosa biofilm from dental implants. Further studies are needed to evaluate the removal of more complex biofilms. Titanium brushes caused significant changes to the implant surface, the effects of which need to be evaluated. Full article
(This article belongs to the Special Issue Recent Advances in Dental Implantology: Part II)
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