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Special Issue "Intestinal Obstruction: Etiology and Pathophysiology, Clinical Presentation and Imaging, Diagnosis and Treatment"

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A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "General Surgery".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 2197

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Dr. Orestis M. Ioannidis

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Guest Editor

4th Academic Department of Surgery, Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, Alexandrou Mihailidi 13, 54640 Thessaloniki, Greece
Interests: acute care surgery; surgical infections; negative pressure wound therapy; vascular access; nutrition; open abdomen; minimally invasive surgery; enhanced
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Dear Colleagues,

Intestinal obstruction is among the most common surgical emergencies worldwide and is considered one of the most serious problems in surgery, with relatively high morbidity and mortality. In 80% of cases, it concerns the small intestine, and in 20%, the large intestine, and it can be incomplete or complete, acute or chronic, high or low. The clinical presentation varies depending on the etiology and level of the obstruction. Imaging studies are of great importance to establish the diagnosis, determine the cause, and guide treatment. Treatment can be either medical or surgical. Today, with the advancement of minimally invasive techniques, surgical treatment in addition to open surgery can be carried out laparoscopically and robotically, and there is great interest in implementing enhanced recovery protocols in the surgical management of these patients. In this Special Issue of the Journal of Clinical Medicine, we will discuss the etiology and pathophysiology, clinical presentation and imaging, diagnosis, differential diagnosis, and treatment of intestinal obstruction. Basic research based on animal models of small and large bowel obstruction as well as epidemiological and clinical studies, observational, retrospective, and prospective as well as reviews are welcome for submission.

Dr. Orestis M. Ioannidis
Guest Editor

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Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

small bowel
large bowel
acute care surgery
intestine
laparoscopic surgery
robotic surgery
minimally invasive surgery
enhanced recovery
endoscopic treatment
fluorescence ICG (indocyanine green) imaging

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Open AccessArticle

The EUPEMEN (EUropean PErioperative MEdical Networking) Protocol for Bowel Obstruction: Recommendations for Perioperative Care

Orestis Ioannidis

Jose M. Ramirez

Javier Martínez Ubieto

Alejandro Bona Enguita

Marta Teresa

and

Elissavet Anestiadou

J. Clin. Med. 2023, 12(13), 4185; https://doi.org/10.3390/jcm12134185 - 21 Jun 2023

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Abstract

Mechanical bowel obstruction is a common symptom for admission to emergency services, diagnosed annually in more than 300,000 patients in the States, from whom 51% will undergo emergency laparotomy. This condition is associated with serious morbidity and mortality, but it also causes a high financial burden due to long hospital stay. The EUPEMEN project aims to incorporate the expertise and clinical experience of national clinical specialists into development of perioperative rehabilitation protocols. Providing special recommendations for all aspects of patient perioperative care and the participation of diverse specialists, the EUPEMEN protocol for bowel obstruction, as presented in the current paper, aims to provide faster postoperative recovery and reduce length of hospital stay, postoperative morbidity and mortality rate. Full article

(This article belongs to the Special Issue Intestinal Obstruction: Etiology and Pathophysiology, Clinical Presentation and Imaging, Diagnosis and Treatment)

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Open AccessFeature PaperCase Report

Intestinal Obstruction for Anisakiasis: Surgical and Physical Therapy Treatment

Fernando Cózar-Bernal

Jorge Góngora-Rodríguez

Carmen Ayala-Martínez

Francisco Javier Martín-Vega

Maria Jesus Vinolo-Gil

and

Manuel Rodríguez-Huguet

J. Clin. Med. 2023, 12(13), 4470; https://doi.org/10.3390/jcm12134470 - 04 Jul 2023

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Abstract

Anisakiasis, a zoonotic disease that can lead to small intestine obstruction, has seen a significant rise in Spain. The country has become the first in Europe with an annual incidence of 8000 cases, primarily due to the popularity of consuming exotic dishes of undercooked or raw fish and the impact of climate change. The clinical presentation of anisakiasis can mimic symptoms of acute appendicitis or intestinal obstruction, leading to potential misdiagnosis. This case report describes a 37-year-old patient with no significant medical history who presented abdominal distension and intense pain in the right lower quadrant. The patient underwent surgery and received physiotherapy treatment, including therapeutic exercises and pulsed-pressure myofascial vacuum therapy, to facilitate functional recovery. The increasing incidence of anisakiasis in Spain underscores the need to consider it in the differential diagnosis of digestive diseases, given the high consumption of poorly prepared or raw fish in the region. Full article

(This article belongs to the Special Issue Intestinal Obstruction: Etiology and Pathophysiology, Clinical Presentation and Imaging, Diagnosis and Treatment)

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Open AccessSystematic Review

The Efficacy of Probiotics, Prebiotics, and Synbiotics in Patients Who Have Undergone Abdominal Operation, in Terms of Bowel Function Post-Operatively: A Network Meta-Analysis

Konstantinos Zapsalis

Savvas Symeonidis

Stefanos Bitsianis

Efstathios Kotidis

Manousos George Pramateftakis

Ioannis Mantzoros

and

Stamatios Angelopoulos

J. Clin. Med. 2023, 12(12), 4150; https://doi.org/10.3390/jcm12124150 - 20 Jun 2023

Cited by 1 | Viewed by 626

Abstract

Background: Abdominal operations may lead to post-operative bowel dysfunction, while administration of probiotics, prebiotics and synbiotics may limit its manifestation. Τhe study aimed to assess the efficacy of probiotics, prebiotics and synbiotics in patients who undergone abdominal operation, in terms of bowel function post-operatively. Methods: PubMed, Scopus, Cochrane Central Register of Controlled Trials (Central), Embase, US Registry of clinical trials, and sources of grey literature were searched. The relative effect sizes were estimated, and we obtained the relative ranking of the interventions using cumulative ranking curves. Results: In total, 30 studies were included in the analysis. For the outcome of post-operative ileus, probiotics was superior to placebo/no intervention (relative risk, RR: 0.38; 95%CI: 0.14–0.98) with the highest SUCRA (surface under the cumulative ranking) value (92.1%). For time to first flatus, probiotics (MD: −0.47; 95%CI: −0.78 to −0.17) and synbiotics (MD: −0.53; 95%CI: −0.96 to −0.09) were superior to placebo/no intervention. For time to first defecation and for post-operative abdominal distension probiotics were superior to placebo/no intervention. For post-operative hospitalization days, synbiotics were superior to placebo/no intervention (MD: −3.07; 95%CI: −4.80 to −1.34). Conclusions: Administration of probiotics in patients who had undergone abdominal surgery reduced the prevalence of post-operative ileus, time to first flatus, time to first defecation, and prevalence of post-operative abdominal distension. Synbiotics reduce time to first flatus and post-operative hospitalization days. Full article

(This article belongs to the Special Issue Intestinal Obstruction: Etiology and Pathophysiology, Clinical Presentation and Imaging, Diagnosis and Treatment)

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