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New Insights into Coronary Artery Disease (CAD)
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New Insights into Coronary Artery Disease (CAD)

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 25 September 2024 | Viewed by 959

Special Issue Editor

Dr. Giuseppe Di Gioia

E-Mail Website
Guest Editor
Cardiac Catheterization Laboratory, Montevergine Clinic, Mercogliano, Italy
Interests: coronary artery disease; coronary physiology; carotid artery stenting; percutaneous treatment of valvular disease

Special Issue Information

Dear Colleagues,

Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide, encompassing a wide range of conditions that span from asymptomatic stable coronary plaque to acute myocardial infarction with hemodynamic or electrical instability.

Pharmaceutical and technological advancements have recently led to a significant improvement in both the medical and interventional treatment of patients with CAD. However, there is still much to do, especially in terms of prevention and in order to improve the long-term outcomes of PCI and stenting.

This Special Issue aims to provide a comprehensive platform for the dissemination of the latest advancements and discoveries related to CAD. By delving into novel insights, this Special Issue aims to enhance our understanding of the complexities of CAD and promote the translation of scientific discoveries into clinical practice.

In this Special Issue, entitled “New Insights into Coronary Artery Disease”, we invite the submission of manuscripts regarding the latest information on the topic, including original clinical studies and reviews.

Dr. Giuseppe Di Gioia
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • coronary artery disease
  • chronic coronary syndrome
  • acute coronary syndrome
  • percutaneous coronary intervention
  • cardiac arrest

Published Papers (1 paper)

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Research

11 pages, 1472 KiB  
Article
Are Thiols Useful Biomarkers for Coronary Collateral Circulation in Patients with Stable Coronary Artery Disease?
by Yasemin Doğan, Yücel Yilmaz, Saban Kelesoğlu, Bekir Calapkorur, Salim Neşelioglu, Özcan Erel and Nihat Kalay
J. Clin. Med. 2023, 12(19), 6361; https://doi.org/10.3390/jcm12196361 - 04 Oct 2023
Cited by 1 | Viewed by 724
Abstract
Our aim was to investigate the relationship between thiol, which is the main component of the antioxidant system, and coronary collateral circulation (CCC). Our patients consisted of people with stable coronary artery disease (sCAD) and total occlusion in at least one vessel ( [...] Read more.
Our aim was to investigate the relationship between thiol, which is the main component of the antioxidant system, and coronary collateral circulation (CCC). Our patients consisted of people with stable coronary artery disease (sCAD) and total occlusion in at least one vessel (n = 249). We divided the patients into two groups, good and poor, according to their CCC degree. We determined that DM, total thiol, and disulfide are independent predictors of poor CCC in multivariate logistic regression analysis (OR: 1.012, 95% CI: 1.008–1.017, p < 0.001; OR: 1.022, 95% CI: 1.000–1.044, p = 0.044; OR: 2.671, 95% CI: 1.238–5.761, p = 0.012, respectively). The ROC analysis showed a cut-off value of 328.7 for native thiol regarding the prediction of poor CCC, with 67.4% specificity and 78% sensitivity. For disulfide, it revealed a cut-off value of 15.1 regarding the prediction of poor CCC, with 57.9% specificity and 69.5% sensitivity. In this study, we detected that the patients with sCAD who developed poor CCC had lower levels of native thiol, total thiol, and disulfide compared to those with good CCC. The most interesting finding of our study is that CCC formation is an effective predictor of the antioxidant cascade rather than the inflammation cascade in sCAD patients. Full article
(This article belongs to the Special Issue New Insights into Coronary Artery Disease (CAD))
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