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Guidelines for the Management of Pulmonary Arterial Hypertension
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Guidelines for the Management of Pulmonary Arterial Hypertension

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Guidelines".

Deadline for manuscript submissions: 20 August 2024 | Viewed by 804

Special Issue Editors

Dr. Roxana Sulica

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Guest Editor
Pulmonary Hypertension, Department of Medicine, Pulmonary Critical Care and Sleep Division, NYU Grossman School of Medicine, NYU Langone Health, New York, NY 10016, USA
Interests: pulmonary vascular disease; pulmonary medicine; critical care
Special Issues, Collections and Topics in MDPI journals
Dr. Himanshu Deshwal

E-Mail Website
Guest Editor
Pulmonary Hypertension Clinic, Section of Pulmonary, Sleep and Critical Care Medicine, Department of Medicine, West Virginia University School of Medicine, Morgantown, WV 26505, USA
Interests: pulmonary hypertension; pulmonary vascular disorders; right ventricular failure; hemodynamics; point-of-care ultrasonography; pulmonary embolism
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Pulmonary arterial hypertension is a serious disease caused by vasoconstriction and remodeling of the pulmonary vasculature, which, in the absence of appropriate therapy, ultimately leads to right ventricular failure and death. Recently published guidelines focus on the new hemodynamic definition of pulmonary hypertension, a new diagnostic algorithm with expedited referrals for severe or complex cases, the role of noninvasive work-up to distinguish among different groups of pulmonary hypertension, and the importance of risk assessment to guide treatment options in both incident and prevalent cases. In this Special Issue, we examine the application of these new concepts in the clinical management of pulmonary arterial hypertension, such as the role of echocardiography in identifying the probablity of pulmonary hypertension, new developments in imaging and exercise testing in the pulmonary hypertension work-up, and the technique of right heart catheterization to correctly identify various clinical phenotypes of pulmonary hypertension. Finally, and importantly, we describe the integrated diagnostic approach and treatment algorithm in patients with pulmonary arterial hypertension.

Dr. Roxana Sulica
Dr. Himanshu Deshwal
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pulmonary arterial hypertension
  • diagnosis
  • treatment
  • echocardiography
  • right heart catheterization

Published Papers (1 paper)

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Research

9 pages, 2023 KiB  
Article
Pelvic Vein Obstruction in Chronic Thromboembolic Pulmonary Hypertension: A Novel Association
by Anjali Vaidya, Anika Vaidy, Mohamad Al-Otaibi, Brooke Zlotshewer, Estefania Oliveros, Huaqing Zhao, Ahmed Sadek, Vladimir Lakhter, Paul R. Forfia and Riyaz Bashir
J. Clin. Med. 2024, 13(6), 1553; https://doi.org/10.3390/jcm13061553 - 08 Mar 2024
Viewed by 588
Abstract
Background: Pelvic venous obstruction (PVO), defined as greater than 50% stenosis or occlusion of pelvic veins, is a known risk factor for deep vein thrombosis (DVT). DVT is a known risk factor for chronic thromboembolic pulmonary hypertension (CTEPH), but the prevalence of PVO [...] Read more.
Background: Pelvic venous obstruction (PVO), defined as greater than 50% stenosis or occlusion of pelvic veins, is a known risk factor for deep vein thrombosis (DVT). DVT is a known risk factor for chronic thromboembolic pulmonary hypertension (CTEPH), but the prevalence of PVO in CTEPH is unknown. Methods: This cross-sectional study at Temple University’s tertiary referral center for Pulmonary Hypertension, Right Heart Failure, and CTEPH sought to identify the presence of PVO in patients with CTEPH who underwent cardiac catheterization, pulmonary angiography, and venography. Results: A total of 193 CTEPH patients were referred for pulmonary angiography, and among these, 148 underwent venography. PVO was identified in 65 (44%) patients. Lower extremity (LE) DVT was associated with PVO (p = 0.004). The severity of pulmonary hypertension was similar with and without PVO (mean pulmonary artery pressure 43.0 ± 10.3 mm Hg vs. 43.8 ± 12.4 mm Hg, p = 0.70), as was the need for pulmonary thromboendarterectomy (69.2% vs. 61.4%, p = 0.32). Conclusions: Pelvic vein obstruction is common and a novel clinical association in patients with CTEPH, particularly in patients with a history of LE DVT. PVO and its role in CTEPH warrants further study, including the potential role of revascularization to mitigate further risk. Full article
(This article belongs to the Special Issue Guidelines for the Management of Pulmonary Arterial Hypertension)
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