Review Special Issue Series: Recent Advances in Pulmonology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Pulmonology".

Deadline for manuscript submissions: closed (25 April 2024) | Viewed by 684

Special Issue Editor


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Guest Editor
Respiratory Translational Research Group, Department of Laboratory Medicine, College of Health and Medicine, University of Tasmania, Launceston, TAS 7248, Australia
Interests: COPD; COVID-19; asthma; idiopathic pulmonary fibrosis (IPF); lung cancer; airway remodelling; effects and mechanisms of inhaled corticosteroids (ICS); effects of electronic nicotine delivery systems; mechanisms of respiratory infections and inflammation; smoking cessation and air pollution
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Special Issue Information

Dear Colleagues,

The Journal of Clinical Medicine (JCM) is now introducing a special review series that will update our clinical and scientific community on the recent advances in pulmonary medicine. We invite state-of-the-art reviews on current topical issues in respiratory medicine, science, and surgery. Pulmonary diseases impose a universal burden that affects hundreds of millions of people. Given the stubborn nature of the established diseases and emerging risks, such as the rise in the number of cases of allergies, vaping, and smoking and the severity of environmental pollution and the current global coronavirus pandemic, the importance of respiratory medicine has never been greater. Chronic lung disease involves multifaceted pathological mechanisms. There is an urgent need to understand these pathological mechanisms. Early disease mechanisms change the disease trajectory in the first phase. Thus, we need novel diagnostic tools to detect these changes. Therapeutics evolve by understanding what is happening. Collectively, this will allow the use of early interventions that will lead to the better management of patients and will enormously inform clinical practice. To answer these important questions and promote future research, we sincerely welcome your submissions to this Special Issue in the JCM.

Dr. Sukhwinder Singh Sohal
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • COPD
  • asthma
  • ILD
  • pulmonary hypertension
  • rare lung diseases
  • lung cancer
  • respiratory infections
  • inflammation
  • pulmonary rehabilitation
  • effects of smoking and vaping
  • pharmacological treatments and clinical trials

Published Papers (1 paper)

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22 pages, 1464 KiB  
Review
Neutrophil Extracellular Traps and Respiratory Disease
by Paul T. King and Lovisa Dousha
J. Clin. Med. 2024, 13(8), 2390; https://doi.org/10.3390/jcm13082390 - 19 Apr 2024
Viewed by 349
Abstract
Extracellular traps made by neutrophils (NETs) and other leukocytes such as macrophages and eosinophils have a key role in the initial immune response to infection but are highly inflammatory and may contribute to tissue damage. They are particularly relevant to lung disease, with [...] Read more.
Extracellular traps made by neutrophils (NETs) and other leukocytes such as macrophages and eosinophils have a key role in the initial immune response to infection but are highly inflammatory and may contribute to tissue damage. They are particularly relevant to lung disease, with the pulmonary anatomy facilitating their ability to fully extend into the airways/alveolar space. There has been a rapid expansion in the number of published studies demonstrating their role in a variety of important respiratory diseases including chronic obstructive pulmonary disease, cystic fibrosis, bronchiectasis, asthma, pneumonia, COVID-19, rhinosinusitis, interstitial lung disease and lung cancer. The expression of NETs and other traps is a specific process, and diagnostic tests need to differentiate them from other inflammatory pathways/causes of cell death that are also characterised by the presence of extracellular DNA. The specific targeting of this pathway by relevant therapeutics may have significant clinical benefit; however, current clinical trials/evidence are at a very early stage. This review will provide a broad overview of the role of NETs and their possible treatment in respiratory disease. Full article
(This article belongs to the Special Issue Review Special Issue Series: Recent Advances in Pulmonology)
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