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Special Issues
Cardiovascular and Neurological Complications of COVID—19
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Cardiovascular and Neurological Complications of COVID—19

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Emergency Medicine".

Deadline for manuscript submissions: closed (27 February 2023) | Viewed by 5203

Special Issue Editor

Dr. Leonardo Roever

E-Mail Website
Guest Editor
1. Department of Clinical Research, Federal University of Uberlândia, Uberlândia, Brazil, MG, Brazil
2. Postgraduate Program in Medicine and Health, Faculty of Medicine of Bahia, Federal University of Bahia, Salvador, BA, Brazil
3. Department of Psychiatry, Faculty of Medicine, University of São Paulo, São Paulo, SP, Brazil
Interests: neurodegenerative diseases; psychiatric disorders; neuroimaging; neurobiology; neuroprogression; inflammation; biomarkers; brain mapping; tractography; neurocir-cuits; meta-analyses
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cardiovascular and neurological diseases continue to be one of the most common chronic diseases worldwide, with a great impact on morbidity and mortality in the population. The importance of these diseases lies in their demand for evidence-based continuous care, access to technology and cutting-edge research for a better understanding and management of them, as well as patient participation in disease control strategies. The new SARS-CoV-2 affected the risk and prognosis of cardiovascular diseases. Their management remains a challenge for healthcare professionals and patients around the world, especially in developing countries. This special issue of the Journal of Clinical Medicine will be dedicated to publishing the best articles that reflect efforts and innovation to better diagnose, measure impact, develop treatments and education for cardiovascular disease and related issues. In this Special Issue, we hope to collect the best original and review articles on various aspects related to diagnosis, prevention, control, treatment, cost-effectiveness, epidemiology, education and other issues related to this very prevalent disease. All submissions will be selected and peer-reviewed to ensure the quality and relevance of the manuscripts.

Dr. Leonardo Roever
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • COVID-19 cardiology neurology outcomes

Published Papers (2 papers)

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Research

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15 pages, 301 KiB  
Article
COVID-19 and Acute Ischemic Stroke Mortality and Clinical Outcomes among Hospitalized Patients in the United States: Insight from National Inpatient Sample
by Monique G. Davis, Karthik Gangu, Sajid Suriya, Babu Sriram Maringanti, Prabal Chourasia, Aniesh Bobba, Alok Tripathi, Sindhu Reddy Avula, Rahul Shekhar and Abu Baker Sheikh
J. Clin. Med. 2023, 12(4), 1340; https://doi.org/10.3390/jcm12041340 - 08 Feb 2023
Cited by 1 | Viewed by 2457
Abstract
Coronavirus-19, primarily a respiratory virus, also affects the nervous system. Acute ischemic stroke (AIS) is a well-known complication among COVID-19 infections, but large-scale studies evaluating AIS outcomes related to COVID-19 infection remain limited. We used the National Inpatient Sample database to compare acute [...] Read more.
Coronavirus-19, primarily a respiratory virus, also affects the nervous system. Acute ischemic stroke (AIS) is a well-known complication among COVID-19 infections, but large-scale studies evaluating AIS outcomes related to COVID-19 infection remain limited. We used the National Inpatient Sample database to compare acute ischemic stroke patients with and without COVID-19. A total of 329,240 patients were included in the study: acute ischemic stroke with COVID-19 (n = 6665, 2.0%) and acute ischemic stroke without COVID-19 (n = 322,575, 98.0%). The primary outcome was in-hospital mortality. Secondary outcomes included mechanical ventilation, vasopressor use, mechanical thrombectomy, thrombolysis, seizure, acute venous thromboembolism, acute myocardial infarction, cardiac arrest, septic shock, acute kidney injury requiring hemodialysis, length of stay, mean total hospitalization charge, and disposition. Acute ischemic stroke patients who were COVID-19-positive had significantly increased in-hospital mortality compared to acute ischemic stroke patients without COVID-19 (16.9% vs. 4.1%, aOR: 2.5 [95% CI 1.7–3.6], p < 0.001). This cohort also had significantly increased mechanical ventilation use, acute venous thromboembolism, acute myocardial infarction, cardiac arrest, septic shock, acute kidney injury, length of stay, and mean total hospitalization charge. Further research regarding vaccination and therapies will be vital in reducing worse outcomes in patients with acute ischemic stroke and COVID-19. Full article
(This article belongs to the Special Issue Cardiovascular and Neurological Complications of COVID—19)

Review

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16 pages, 3227 KiB  
Review
Cardiovascular and Neurological Complications of COVID-19: A Narrative Review
by Luma Ornelas Sousa Rêgo, Lara Landulfo Alves Braga, Gustavo Sampaio Vilas-Boas, Maiana Santos Oliveira Cardoso and Andre Rodrigues Duraes
J. Clin. Med. 2023, 12(8), 2819; https://doi.org/10.3390/jcm12082819 - 12 Apr 2023
Cited by 3 | Viewed by 2135
Abstract
A novel coronavirus emerged in China in late 2019 as a disease named coronavirus disease 2019. This pathogen was initially identified as causing a respiratory syndrome, but later, it was found that COVID-19 could also affect other body systems, such as the neurological [...] Read more.
A novel coronavirus emerged in China in late 2019 as a disease named coronavirus disease 2019. This pathogen was initially identified as causing a respiratory syndrome, but later, it was found that COVID-19 could also affect other body systems, such as the neurological and cardiovascular systems. For didactic purposes, cardiovascular and neurological manifestations of SARS-CoV-2 have been classified in three different groups: acute complications, late complications, and post-vaccine complications. Therefore, the following study has the goal to summarize and disseminate the present knowledge about the cardiovascular and neurological manifestations of COVID-19 based on the latest and most up-to-date data available and, thus, promote more prepared medical care for these conditions as the medical team is updated. Based on what is brought on this revision and its understanding, the medical service becomes more aware of the causal relationship between some conditions and COVID-19 and can better prepare for the most prevalent conditions to associate and, consequently, to treat patients earlier. Therefore, there is a chance of better prognoses in this context and the need to increase the number of studies about complications related to SARS-CoV-2 infection for a better understanding of other associated conditions. Full article
(This article belongs to the Special Issue Cardiovascular and Neurological Complications of COVID—19)
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