Management, Diagnosis and Pathophysiology of Antiphospholipid Syndrome: Current Practice and Future Perspectives—Volume II
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Hematology".
Deadline for manuscript submissions: 31 October 2024 | Viewed by 3155
Special Issue Editor
Interests: antiphospholipid syndrome; pregnancy morbidity; antiphospholipid antibodies; resistance to activated protein c; venous thrombosis; stroke
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antiphospholipid syndrome (APS) is an autoimmune disorder associated with life-threatening complications that, despite therapeutic advances, continues to cause significant mortality and morbidity. APS-associated clinical manifestations are heterogeneous and diverse, varying from venous and arterial thrombosis to catastrophic APS (CAPS) and pregnancy morbidity. APS is often associated with other autoimmune conditions, such as systemic lupus erythematosus, leading to a more severe course of disease. Life-long anticoagulation with vitamin K antagonists remains the standard treatment for thrombotic APS, but it is often associated with recurrences and failures and is not applicable to all manifestations of APS. Unfortunately, the diagnosis and management of APS continue to be challenging for clinicians.
At the same time and despite various mechanisms having been proposed as key components in the pathophysiology of APS, and many more are emerging, their precise contributions in the clinical manifestations of APS remain unknown. This heterogeneity underlying the pathophysiology of APS suggests that a single therapy is unlikely to be effective in all patients.
The scope of this Special Issue, which will include original papers and reviews, is to provide an updated overview of the progress and advances in the treatment and pathophysiology of APS that will aid in the accurate diagnosis and management of this devasting disease to prevent its deleterious consequences.
Dr. Maria Efthymiou
Guest Editor
Manuscript Submission Information
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Keywords
- antiphospholipid syndrome
- management
- treatment
- pathophysiology
- diagnostic tests
