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Advanced Endoscopic Technology for Digestive Diseases
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Advanced Endoscopic Technology for Digestive Diseases

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 15 June 2024 | Viewed by 3235

Special Issue Editor

Dr. Priya K. Simoes

E-Mail Website
Guest Editor
Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Interests: abdominal pain; ulcers; diarrhea; cancer; jaundice; endoscopy

Special Issue Information

Dear Colleagues,

There are huge advances being made in gastroenterology, and especially the field of advanced endoscopy, every year. Therapeutic endoscopy has transformed the field of gastroenterology by providing a safe, effective, and minimally invasive way to diagnose and treat a wide range of gastrointestinal disorders.

Endoscopic submucosal dissection, endoscopic ultrasound, and new imaging techniques have revolutionized the way in which we treat benign and malignant gastrointestinal diseases. Artificial intelligence is changing the landscape of this field, with wide-reaching applications which range from improving adenoma detection rates during colonoscopy, to aiding the management of malignant biliary strictures during cholangioscopy.

The aim of this Special Issue is to explore the novel advances in the field of advanced endoscopy and to discuss the ways in which they can improve our daily clinical practice of gastroenterology.

The articles in this Special Issue focus on the latest advances in the field of therapeutic endoscopy and cover a wide range of topics including diagnostic and therapeutic procedures, as well as new devices and instruments and novel techniques for visualization, which are transforming our approach to patient care.

Dr. Priya K. Simoes
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • endoscopic ultrasound
  • endoscopic submucosal dissection
  • biliary
  • artificial intelligence
  • natural language processing

Published Papers (4 papers)

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15 pages, 6534 KiB  
Article
Partial Stent-in-Stent Method with an Uncovered Self-Expandable Metallic Stent for Unresectable Malignant Hilar Bile Duct Obstruction
by Takuya Shimosaka, Yohei Takeda, Taro Yamashita, Yuta Seki, Shiho Kawahara, Takayuki Hirai, Noriyuki Suto, Yuri Sakamoto, Wataru Hamamoto, Hiroki Koda, Takumi Onoyama, Kazuya Matsumoto, Kazuo Yashima, Hajime Isomoto and Naoyuki Yamaguchi
J. Clin. Med. 2024, 13(3), 820; https://doi.org/10.3390/jcm13030820 - 31 Jan 2024
Viewed by 693
Abstract
(1) Background: There is controversy regarding stent placement for unresectable malignant hilar biliary obstruction (UMHBO). We mainly use the partial stent-in-stent (PSIS) method with an uncovered self-expandable metallic stent (UCSEMS) based on the drainage area and patency period. In this study, we investigated [...] Read more.
(1) Background: There is controversy regarding stent placement for unresectable malignant hilar biliary obstruction (UMHBO). We mainly use the partial stent-in-stent (PSIS) method with an uncovered self-expandable metallic stent (UCSEMS) based on the drainage area and patency period. In this study, we investigated the usefulness and safety of the PSIS method. (2) Methods: In total, 59 patients who underwent the PSIS method for UMHBO at our hospital were included in the study. The technical success rate, clinical success rate, time to recurrent biliary obstruction (TRBO) and overall survival (OS) from the first placement, factors affecting TRBO and OS, and early complications within 30 days after the procedure were evaluated retrospectively. (3) Results: The technical and clinical success rates were 100% and 96.6%, respectively, with a TRBO of 121 days [95% confidence interval: 82–231] and an OS of 194 days [95% confidence interval: 113–305] after the first placement. Early complications occurred in nine patients (15.3%), including five cases of cholangitis, three cases of pancreatitis, and one case of cholecystitis. (4) Conclusions: The PSIS method for UMHBO is safe and useful with high technical and clinical success rates. Full article
(This article belongs to the Special Issue Advanced Endoscopic Technology for Digestive Diseases)
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10 pages, 209 KiB  
Article
Esophageal Endoscopic Submucosal Dissection in Older Patients Is Safe and Feasible: A Retrospective Single-Center Cohort Study in the United States
by Mako Koseki, Makoto Nishimura, Jacques C. Beauvais, Tarek Nammour, Sayaka Nagao and Mark A. Schattner
J. Clin. Med. 2024, 13(1), 228; https://doi.org/10.3390/jcm13010228 - 30 Dec 2023
Viewed by 622
Abstract
Background: Endoscopic submucosal dissection (ESD) is a well–established method for treating early esophageal carcinomas. However, data on the safety and efficacy of esophageal ESD in older patients in the United States are limited. Methods: This retrospective study investigated the outcomes of esophageal ESD [...] Read more.
Background: Endoscopic submucosal dissection (ESD) is a well–established method for treating early esophageal carcinomas. However, data on the safety and efficacy of esophageal ESD in older patients in the United States are limited. Methods: This retrospective study investigated the outcomes of esophageal ESD in patients aged ≥80 years and included those who underwent esophageal ESD between June 2018 and April 2023 at a single center in the United States. Patients were divided into two age groups for comparison: ≥80 and <80 years. Treatment outcomes and complications were evaluated and compared between these groups. Results: A total of 53 cases of esophageal ESD for malignant neoplasms were included, with 12 patients in the ≥80 years age group. No significant differences were observed in the patients’ background and characteristics, except for a prior history of interventions (p = 0.04). The en bloc resection rate was 100% in both groups. The R0 resection rate was lower in the ≥80 years age group (75% vs. 88%). There were no complications requiring additional intervention in the ≥80 years age group, such as post–ESD bleeding, perforation, mediastinal emphysema, or pneumonia. Conclusions: Esophageal ESD may be a safe and feasible procedure for treating esophageal carcinomas in older patients. Full article
(This article belongs to the Special Issue Advanced Endoscopic Technology for Digestive Diseases)
11 pages, 937 KiB  
Article
Endoscopic Submucosal Dissection for Treatment of Early-Stage Cancer or Precancerous Lesion in the Upper Gastrointestinal Tract in Patients with Liver Cirrhosis
by Yuyong Tan, Yumin Qing, Deliang Liu and Jian Gong
J. Clin. Med. 2023, 12(20), 6509; https://doi.org/10.3390/jcm12206509 - 13 Oct 2023
Cited by 2 | Viewed by 830
Abstract
(1) Background: Endoscopic submucosal dissection (ESD) has been widely accepted as the standard method for treating early-stage cancer or precancerous lesions in the upper gastrointestinal tract; however, it may be difficult in patients with liver cirrhosis due to clinical challenges such as coagulation [...] Read more.
(1) Background: Endoscopic submucosal dissection (ESD) has been widely accepted as the standard method for treating early-stage cancer or precancerous lesions in the upper gastrointestinal tract; however, it may be difficult in patients with liver cirrhosis due to clinical challenges such as coagulation dysfunction, presence of gastroesophageal varices, etc. We aimed to demonstrate the safety and efficacy of ESD in these populations. (2) Methods: The clinical data of patients were retrospectively collected and analyzed. Inclusion criteria of the study were: a. patients with liver cirrhosis; b. patients who underwent ESD; c. patients who were diagnosed with early-stage cancer or precancerous lesions in the upper gastrointestinal tract. (3) Results: Eight patients were enrolled from April 2019 to April 2023, of whom three were male and five were female, with ages ranging from 43 to 70 years old. Seven lesions were located in the stomach and one other lesion was in the esophagus. ESD was performed successfully in all eight patients, and the resected lesion size ranged from 2 to 6 cm. Only one patient encountered postoperative complications, namely, chest pain and fever. No recurrence was noticed during a follow-up of 3 to 45 months. (4) Conclusions: ESD may serve as a safe and effective method for treating upper gastrointestinal early-stage cancer or precancerous lesions in patients with liver cirrhosis. Full article
(This article belongs to the Special Issue Advanced Endoscopic Technology for Digestive Diseases)
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12 pages, 553 KiB  
Systematic Review
The Prevalence, Etiology and Treatment of Gastroduodenal Ulcers and Perforation: A Systematic Review
by Rizki Amalia, Amie Vidyani, Reny I’tishom, Wiwin Is Efendi, Edwin Danardono, Bogi Pratomo Wibowo, Muhammad Lutfi Parewangi, Muhammad Miftahussurur and Hoda M. Malaty
J. Clin. Med. 2024, 13(4), 1063; https://doi.org/10.3390/jcm13041063 - 13 Feb 2024
Viewed by 797
Abstract
(1) Background: Gastroduodenal perforation (GDP) is a life-threatening condition caused by a spontaneous or traumatic event. Treatment should be based on the mechanism of damage, timing, location, extent of the injury, and the patient’s clinical condition. We aimed to examine several etiologic factors [...] Read more.
(1) Background: Gastroduodenal perforation (GDP) is a life-threatening condition caused by a spontaneous or traumatic event. Treatment should be based on the mechanism of damage, timing, location, extent of the injury, and the patient’s clinical condition. We aimed to examine several etiologic factors associated with gastroduodenal perforation and to search for the best method(s) for its prevention and treatment. (2) Methods: We conducted extensive literature reviews by searching numerous studies obtained from PubMed, Science Direct, and Cochrane for the following keywords: gastroduodenal perforation, Helicobacter pylori, NSAIDs’ use, side effects of GDP, laparoscopy, and surgery. The primary outcome was the reported occurrence of GDP. (3) Results: Using keywords, 883 articles were identified. After applying the inclusion and exclusion criteria, 53 studies were eligible for the current analyses, with a total number of 34,692 gastroduodenal perforation cases. Even though the risk factors of gastroduodenal perforation are various, the prevalence of H. pylori among patients with perforation is considerably high. As technology develops, the treatment for gastric perforation will also improve, with laparoscopic surgery having a lower mortality and complication rate compared to open surgery for GDP treatment. (4) Conclusions: H. pylori infection plays the most significant role in GDP, more than NSAIDs, surgery, chemotherapy, or transplantation. Treatment of H. pylori infection is essential to decrease the prevalence of GDP and speed up its recovery. However, urgent cases require immediate intervention, such as laparoscopic or open surgery. Full article
(This article belongs to the Special Issue Advanced Endoscopic Technology for Digestive Diseases)
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