Male Sexual and Reproductive Health: Clinical Aspects, Metabolic Profile, Environmental Factors and Lifestyle

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Reproductive Medicine & Andrology".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 7170

Special Issue Editor


E-Mail Website
Guest Editor
1. Andrology Unit, Department of Clinical and Molecular Medicine, "Sapienza" University of Rome, Sant'Andrea Hospital, via di Grottarossa 1038, Rome, Italy
2. AIED Center for Reproductive Medicine, Via Toscana 30, Rome, Italy
Interests: erectile dysfunction; sexual function; hypogonadism; infertility; semen analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Male Sexual and Reproductive Health is an important issue worldwide. Approximately 20–30% of adult men have at least one sexual dysfunction (SD). Among these, erectile dysfunction (ED) and premature ejaculation (PE) are the most frequent. In addition, couple infertility, which is defined as the inability to conceive after at least 12 months of regular unprotected sexual intercourse, affects 15–20% of couples worldwide.

Alongside aging and organic causes, i.e., vasculogenic, neurogenic, endocrinological (as hypogonadism and hyperprolactinemia), metabolic (diabetes and dyslipidemia), osteoporosis, etc., also psychological causes could impair Sexual and Reproductive Health.

In addition, also incorrect lifestyle (i.e., psychological stress, inadequate physical activity, caffeine and smoking abuse, high scrotal temperature, prolonged mobile telephone use, etc.), occupational/environmental factors and nutritional habits could play an important role both in the development of SD as well as infertility.

The investigation of all these aspects could be useful to ameliorate the prevention, diagnosis and treatment of the patients.

Therefore, this Special Issue will explore SD and infertility etiology, comorbidity and management based on a combination of original research and review papers.

Topics will include epidemiology, causes, diagnosis and treatments of SD and infertility; lifestyle’s role, nutritional habits, and occupational and environmental factors on Sexual and Reproductive Health.

Dr. Fernando Mazzilli
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • male sexual dysfunction
  • reproductive health
  • erectile dysfunction
  • premature ejaculation
  • infertility
  • epidemiology
  • causes
  • diagnosis
  • treatments
  • environmental factors
  • lifestyle

Published Papers (3 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

17 pages, 2867 KiB  
Article
Muscle Strength and Male Sexual Function
by Anders Flataker Viken, Silver Peeter Siiak, Vivi Schlünssen, Elin Helga Thorarinsdottir, Svein Magne Skulstad, Sanjay Gyawali, Randi Jacobsen Bertelsen and Francisco Gómez Real
J. Clin. Med. 2024, 13(2), 426; https://doi.org/10.3390/jcm13020426 - 12 Jan 2024
Viewed by 2956
Abstract
Sexual dysfunction, in particular erectile dysfunction, is a common complaint among aging men. Obesity, diabetes, hypertension, and smoking are shown to be independent risk factors for erectile dysfunction, while cardiorespiratory fitness is shown to be protective. Less is known about the role of [...] Read more.
Sexual dysfunction, in particular erectile dysfunction, is a common complaint among aging men. Obesity, diabetes, hypertension, and smoking are shown to be independent risk factors for erectile dysfunction, while cardiorespiratory fitness is shown to be protective. Less is known about the role of muscle strength in male sexual function. Our objective was to study the association between male sexual function and typical cardiovascular risk factors, together with exercise and muscle strength. We included data from the fourth wave of the RHINE study. Data on anthropometrics, exercise habits, diseases, muscle strength, and sexual function were collected using questionnaires, including the Aging Males’ Symptoms (AMS) scale. We used multivariable logistic regression analysis to measure the association between sexual function and body mass index (BMI), age, smoking, diabetes, hypertension, exercise and muscle strength status. We included 2116 men aged 48–75 from four Nordic-Baltic countries. BMI, age, smoking, diabetes, and hypertension were found to be associated with higher odds of reporting decreased sexual function, while reporting intact muscle strength was associated with lower odds. In a large Nordic-Baltic male study population, we show that known cardiovascular risk factors are associated with decreased sexual function, while reporting intact muscle strength is associated with lower odds of reporting decreased sexual function. Full article
Show Figures

Figure 1

11 pages, 857 KiB  
Article
Impact of Internet Addiction, Social Media Use and Online Pornography on the Male Sexual Function in Times of the COVID-19 Pandemic
by Anna Pawlikowska-Gorzelańczyk, Daniel Fichte, Julia Rozmus, Piotr Roder, Remigiusz Flakus, Ewa Szuster, Kinga Brawańska, Małgorzata Biernikiewicz, Małgorzata Sobieszczańska, Agnieszka Rusiecka and Dariusz Kałka
J. Clin. Med. 2023, 12(19), 6407; https://doi.org/10.3390/jcm12196407 - 08 Oct 2023
Cited by 1 | Viewed by 1738
Abstract
Over recent decades, the use of the Internet has dramatically increased, both for professional purposes and entertainment. We investigated the link between social media use, video games, dating apps, and pornography on men’s sexual health, which makes life easier, but also carries potential [...] Read more.
Over recent decades, the use of the Internet has dramatically increased, both for professional purposes and entertainment. We investigated the link between social media use, video games, dating apps, and pornography on men’s sexual health, which makes life easier, but also carries potential threats. Online surveys including The International Index of Erectile Function (IIEF) and Bergen Social Media Addiction Scale questionnaires were spread to young, sexually active men. We asked about demographics, sexual activity, and the use of social media, video games, dating apps, and pornography. We enrolled 702 men aged 18 to 60 years (mean 24.06 ± 5.70). In general, 1.6% of men were exposed to social media addiction. Social media addiction had a negative impact on IIEF scores, while pornography in general had no impact on men’s sexual health. However, more extensive use of pornography was correlated with lower IIEF scores. A negative impact of dating apps use on the IIEF score was also found but the correlation was weak (p = 0.049). No correlation was found between playing games and IIEF. We conclude that social media addiction negatively affected men’s sexual functioning during the COVID-19 pandemic. The development of strategies for the safe use of the Internet and dissemination of this knowledge through social media campaigns can help young people to recognize the first symptoms of social media addiction. Full article
Show Figures

Figure 1

13 pages, 1617 KiB  
Article
Paternal Age Matters: Association with Sperm Criteria’s- Spermatozoa DNA Integrity and Methylation Profile
by Marwa Lahimer, Debbie Montjean, Rosalie Cabry, Severine Capelle, Elodie Lefranc, Véronique Bach, Mounir Ajina, Habib Ben Ali, Hafida Khorsi-Cauet and Moncef Benkhalifa
J. Clin. Med. 2023, 12(15), 4928; https://doi.org/10.3390/jcm12154928 - 27 Jul 2023
Cited by 3 | Viewed by 1993
Abstract
Advanced age has been reported to negatively affect sperm parameters and spermatozoa DNA integrity. A decline in sperm criteria was also associated with altered epigenetic marks such as DNA methylation with a potential downstream impact on in vitro fertilization success and clinical outcomes. [...] Read more.
Advanced age has been reported to negatively affect sperm parameters and spermatozoa DNA integrity. A decline in sperm criteria was also associated with altered epigenetic marks such as DNA methylation with a potential downstream impact on in vitro fertilization success and clinical outcomes. The aim of the present retrospective study was to clarify the association between advanced paternal age (APA) and sperm parameters, DNA integrity and DNA methylation profile. A total of 671 patients consulting for infertility underwent sperm analysis, sperm DNA integrity assessment and methylation level measurement. The principal finding was that individuals over 40 years of age exhibit a significant increase in DNA fragmentation levels compared to the younger group (15% versus 9%, respectively, p = 0.04). However, there was no significant difference in DNA decondensation and sperm parameters in association with APA. In addition, a drop in the global methylation level was also found in men over 40 years (6% in the young group versus 2% in the old group, p = 0.03). As a conclusion, men over 40 years are at higher risk of elevated sperm DNA fragmentation and lower methylation level. Based on these observations, it is recommended that the assessment of sperm DNA fragmentation should be taken into consideration particularly after the age of 40. Our findings support the idea that paternal age is a crucial factor that should not be neglected during fertility evaluation and treatment since it is associated with epigenetics changes in sperm. Although the underlying mechanism remains to be clarified, we believe that environmental and professional exposure factors are likely involved in the process. Full article
Show Figures

Figure 1

Back to TopTop