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The Era of New Assisted Reproductive Technology (ART)
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The Era of New Assisted Reproductive Technology (ART)

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".

Deadline for manuscript submissions: 25 June 2024 | Viewed by 2236

Special Issue Editor

Dr. Iori Kisu

E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan
Interests: uterus transplantation; gynecological cancer; Mayer–Rokitansky–Küster–Hauser syndrome; uterine factor infertility; nonhuman primates
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Since the birth of Louise Brown in 1978, assisted reproductive technology (ART) has been a mainstay of fertility treatment. Advances in various types of ART have brought the gospel to many infertile couples. In recent years, techniques for transplanting uterine or ovarian tissue have been developed, which are being positioned as an important new procedure for fertility preservation. Furthermore, regenerative medicine for the uterus or vagina and organoid research for female reproductive organs are also underway. In addition, ART is an essential technique for juvenile cancer survivors in order to preserve fertility, including women that have undergone radical trachelectomy for cervical cancer. Thus, the era of new ART has arrived; this technology will be indispensable in the future, bringing advantages to many infertile patients.

This Special Issue welcomes review and original research articles highlighting the recent ART advances in the field of reproductive medicine or gynecological oncology, with the aim of increasing our understanding and addressing future clinical challenges.

Dr. Iori Kisu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • assisted reproductive technology
  • fertility preservation
  • uterine factor infertility
  • uterus transplantation
  • surrogacy
  • ovarian tissue transplantation
  • ovarian tissue cryopreservation
  • cervical cancer
  • radical trachelectomy
  • bioengineering
  • tissue engineering
  • uterine regeneration
  • oocyte cryopreservation
  • in vitro fertilization

Published Papers (1 paper)

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Review

12 pages, 249 KiB  
Review
Graft Failure after Uterus Transplantation in 16 Recipients: A Review
by Iori Kisu, Risa Matsuda, Tetsuro Shiraishi, Ryoma Hayashi, Yusuke Matoba, Masato Tamate and Kouji Banno
J. Clin. Med. 2023, 12(5), 2032; https://doi.org/10.3390/jcm12052032 - 03 Mar 2023
Cited by 1 | Viewed by 1848
Abstract
Uterus transplantation (UTx) is now an alternative to surrogacy and adoption for women with uterine factor infertility to have children; however, there are still unresolved clinical and technical issues. One of these is that the graft failure rate after transplantation is somewhat higher [...] Read more.
Uterus transplantation (UTx) is now an alternative to surrogacy and adoption for women with uterine factor infertility to have children; however, there are still unresolved clinical and technical issues. One of these is that the graft failure rate after transplantation is somewhat higher than that of other life-saving organ transplants, which is a critical concern. Herein, we summarize the details of 16 graft failures after UTx with living or deceased donors using the published literature in order to learn from these negative outcomes. To date, the main causes of graft failure are vascular factors (arterial and/or venous thrombosis, atherosclerosis, and poor perfusion). Many recipients with thrombosis develop graft failure within one month of surgery. Therefore, it is necessary to devise a safe and stable surgical technique with higher success rates for further development in the UTx field. Full article
(This article belongs to the Special Issue The Era of New Assisted Reproductive Technology (ART))
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