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Advances in the Diagnosis and Treatment of Cardiac Arrhythmias
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Advances in the Diagnosis and Treatment of Cardiac Arrhythmias

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 18 June 2024 | Viewed by 1424

Special Issue Editors

Dr. Roberto Rordorf

E-Mail Website
Guest Editor
Cardiac Intensive Care Unit, Arrhythmia and Electrophysiology and Experimental Cardiology, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy
Interests: arrhythmias; transcatheter cardiac ablation; neuromodulation and radiotherapy of cardiac arrhythmias
Dr. Enrico Baldi

E-Mail Website
Guest Editor
Arrhythmia and Electrophysiology Unit, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
Interests: arrhythmias; neuromodulation; implantable cardioverter–defibrillator; out-of-hospital cardiac arrest; cardiopulmonary resuscitation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cardiac arrhythmias include a great variety of clinical conditions, from the most benign, such as isolated extra beats, to the most life-threatening conditions that can lead to ventricular fibrillation and sudden cardiac death. Our knowledge about the mechanisms of the genesis and perpetuation of cardiac arrhythmias has evolved dramatically in recent years. In parallel, the clinical portfolio for the treatment of cardiac arrhythmias has been enriched significantly, and cardiologists today have different potential “weapons” to help patients with cardiac arrhythmias. Anti-arrhythmic drugs, transcatheter cardiac ablation, pacemakers, and defibrillators are established and effective treatments that are extensively used worldwide in everyday clinical practice. Nonetheless, the results, especially for the treatment of the most prevalent arrhythmias, such as atrial fibrillation and ventricular arrhythmias, are still suboptimal. Personalized therapy, neuromodulation and radiotherapy of cardiac arrhythmias are among the most promising new potential treatments that have recently emerged. These new frontiers may significantly change the clinical approach to cardiac arrhythmias in the near future.

The aim of this Special Issue is to host original and review contributions on the diagnosis and treatment of cardiac arrhythmias. This issue should provide readers with a comprehensive overview of established therapies but also help to take the first steps into the future in the fascinating and complex world of cardiac arrhythmias.

Dr. Roberto Rordorf
Dr. Enrico Baldi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • atrial fibrillation
  • arrhythmia surgery
  • CIED therapy
  • neuromodulation
  • radiotherapy of cardiac arrhythmias
  • cardiac ablation
  • ventricular arrhythmias
  • anti-arrhythmic drugs
  • pacemakers
  • defibrillators

Published Papers (1 paper)

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Research

11 pages, 616 KiB  
Article
Clinical Characteristics of Atrial Flutter and Its Response to Pharmacological Cardioversion with Amiodarone in Comparison to Atrial Fibrillation
by Maciej T. Wybraniec, Kamil Górny, Kamil Jabłoński, Julia Jung, Kiryl Rabtsevich, Przemysław Szyszka, Fabian Wesołek, Karolina Bula, Małgorzata Cichoń, Wojciech Wróbel and Katarzyna Mizia-Stec
J. Clin. Med. 2023, 12(13), 4262; https://doi.org/10.3390/jcm12134262 - 25 Jun 2023
Cited by 1 | Viewed by 1083
Abstract
Background: Unlike atrial fibrillation (AF), atrial flutter (AFl) is thought to be relatively refractory to pharmacological cardioversion (PC), but the evidence is scarce. The aim of this study was to evaluate the clinical characteristics and efficacy of the PC of AFl with amiodarone [...] Read more.
Background: Unlike atrial fibrillation (AF), atrial flutter (AFl) is thought to be relatively refractory to pharmacological cardioversion (PC), but the evidence is scarce. The aim of this study was to evaluate the clinical characteristics and efficacy of the PC of AFl with amiodarone in comparison to AF. Materials and methods: This retrospective study covered 727 patients with urgent consult for AF/AFl in a high-volume emergency department between 2015 and 2018. AFl was diagnosed in 222 (30.5%; median age: 68 (62; 75) years; 65.3% men). In a nested case-control study, 59 control patients with AF, matched in terms of age and sex with 60 AFl patients, were subject to PC with amiodarone. The primary endpoint was return of sinus rhythm confirmed using a 12-lead ECG. Results: The AFl population had a median CHA2DS2-VASc score of 3 (2; 4) and episode duration of 72 h (16; 120). In the AFl cohort, 36% of patients were initially subject to PC, 33.3% to electrical cardioversion (EC) and 40.5% to catheter ablation. In comparison to the AF group, the AFl patients required a longer hospitalization time, had a higher rate of EC (p < 0.001) and less frequent use of PC (p < 0.001) and, lower left ventricular ejection fraction (p < 0.001) and more pronounced cardiovascular risk factors. The efficacy of PC with amiodarone was significantly lower in AFl than AF group (39% vs. 65%, relative risk (RR) 0.60, p = 0.007). Conclusions: AFl patients shared a greater burden of comorbidities than AF patients, while the efficacy of PC in AFl was low. Patients should be initially managed with primary electrical cardioversion. Full article
(This article belongs to the Special Issue Advances in the Diagnosis and Treatment of Cardiac Arrhythmias)
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