Role of Microglia in Several Encephalopathies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 100
Special Issue Editor
Interests: neuroscience; microglia; epilepsy; neuroprotection; tauopathy; neuroinflammation; neurological disorders; Dravet syndrome
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Microglial cells, which are the resident macrophages of the central nervous system (CNS), play key functions in several processes, including developmental supernumerary synapse pruning and immature neuron apoptosis. Microglia also play an essential role in the response to insults and infections of the CNS. In addition, several factors such as neuronal disorders, nutritional and hormonal deficits, and maternal immune activation that interfere with the homeostasis of the CNS, directly impact microglia differentiation, leading to microglial inflammatory activation. Moreover, this microglial inflammatory response likely plays an important role in the long-term consequences and comorbidities of encephalopathies, which are associated with massive microglial inflammation.
In this Special Issue, we will focus on the recent literature concerning microglial function in certain types of encephalopathy-associated neuroinflammation, such as epilepsy, autistic spectrum disorders, sepsis, etc.
Dr. Nadia Soussi-Yanicostas
Guest Editor
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Keywords
- neuroinflammation
- encephalopathy-associated neuroinflammation
- microglia
- epilepsy
- autistic spectrum disorders
- sepsis-associated encephalopathy
- brain development
- environmental factors
- microglial activation
