Molecular Research in Human Stem Cells
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 28 June 2024 | Viewed by 128
Special Issue Editors
Interests: mesenchymal stem cells; cardiovascular disease; atherosclerosis; microRNA; cell differentiation; endothelial to mesenchymal transition (End-MT); inflammation; PPAR-γ
Interests: vascular; stem cells; regenerative medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Stem cells constitute a reservoir of pluripotent cells, capable of differentiating into multiple specialized cell types, and meanwhile, they are endowed with self-renewal to continue the stem cell niche. The stem cell differentiation process is tightly regulated at several levels, like the chemokine/growth factor amount within the microenvironment and the molecular switchers. In this category, transcription factors, signal transduction pathways, microRNA (miRNA) and epigenetics (i.e., DNA methylation, acetylation, phosphorylation) are critical fine tuners of stem cell behavior and phenotypes, including the malignant fate. Therefore, investigating the main mechanisms that govern stem cell biology and fate decision would be promising for translational purposes, bridging the gap between the therapeutic potential and the involvement of stem cells in human disease.
This Special Issue of IJMS will cover the molecular regulatory mechanisms that shape stem cell properties and phenotypes, including in the pathological setting. Biomolecular experiments exploring the transcriptional switchers and miRNAs in stem cell biology are welcome.
Dr. Carmen Ciavarella
Dr. Sabrina Valente
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- stem cells
- mesenchymal stem cells
- miRNA
- differentiation
- self-renewal
- inflammation
- transcription factors
- senescence
- extracellular vesicles
