Oxidative Stress, Ferroptosis and Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 280
Special Issue Editor
2. Quality Control Unit, University Hospital of Sassari (AOU), 07100 Sassari, Italy
Interests: biochemical and epigenetic, and genetic markers of human longevity; inflammatory biomarkers and chronic diseases; oxidative stress and chronic diseases; circulating tumor biomarkers; endothelial dysfunction biomarkers; analytical separation methods
Special Issue Information
Dear Colleagues,
This Special Issue on oxidation, ferroptosis, and cancer aims to address the relationships between oxidative stress, ferroptosis, and cancer. Ferroptosis is an atypical form of regulated cell death characterized by the iron-dependent oxidative destruction of cell membranes as a result of the failure of the antioxidant system hindawi.com. Increased oxidative stress (ROS) is a hallmark of cancer, and ferroptosis links nutritional metabolism and redox biology. Targeting ferroptosis could be an effective and selective way of performing cancer therapy.
Topics of interest include:
- The specific pathways involved in ROS and ferroptosis to develop diagnostic and therapeutic approaches for cancer therapy;
- The role of lipid mediators in ferroptosis and their importance in developing new strategies for understanding metabolic pathways in cancer cells;
- The investigation of epigenetics and the regulation of ferroptosis, examining the role of DNA methylation, RNA methylation, and post-translational modifications in the regulation of ferroptosis;
- The development of new strategies combining immunotherapy and proferroptotic treatment to address drug-resistant cancer therapy.
This Special Issue aims to provide a comprehensive overview of the latest findings and developments in ferroptosis and cancer, focusing on metabolic pathways, oxidation regulation, and immune response. In addition, potential diagnostic and therapeutic applications for cancer treatment are explored.
Prof. Dr. Ciriaco Carru
Guest Editor
Manuscript Submission Information
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Keywords
- oxidative stress
- ferroptosis
- cancer
- frailty
