Immunoregulation within the Tumor Microenvironment: Special Emphasis on Macrophages and NK Cells
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 June 2024 | Viewed by 277
Special Issue Editor
Interests: acute leukemia; phase 1 clinical studies; translational research
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The tumor microenvironment (TME) has a major impact on solid and hematological tumors as well as on the immune system itself. It is still poorly understood which complex immunological and molecular mechanisms control these changes? In this Special Issue, we aim to collate papers which investigate mechanisms leading to functional changes in tumor-associated immune cell subsets such as T cells, NK cells, or macrophages within the TME. A focus here will be on new immunological target structures, transcription factors, and molecular pathways that have the therapeutic potential to restore the function of immune cells. Based on the current state of research, it seems particularly promising to test combined therapeutic approaches.
Prof. Dr. Walter Fiedler
Guest Editor
Manuscript Submission Information
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Keywords
- microenvironment
- macrophages
- dendritic cells
- NK cells
- immune cells
- MSCs
