Developments in the Study of Peptide or Protein Interactions with Model BioMembrane Systems
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 April 2024 | Viewed by 141
Special Issue Editor
Special Issue Information
Dear Colleagues,
Cell membranes are complex bilayer assemblies that perform the contradictory functions of separating the internal constituents of the cell from the cytoplasm, while also enabling the transfer of molecules across the membrane to perform functions essential to life. The major constituents of cell membranes are phospholipids, sterols and proteins. Even this is a very reductionist view, with many variations in size, shape, charge and function being possible within this group of compounds. The simplest model employed consists of a single phospholipid assembled, in some manner, into a bilayer system. There have been significant advancements in the development of more complex model membrane systems, some from the perspective of combining individual components and others from the perspective of reconstituting membrane extracts into a solution for study or deposition onto a surface.
This Special Issue will highlight advances in both the development of more complex realistic model systems, their structural study, and research that probes the mechanism of interaction of drugs, peptides or proteins that target the cell membrane. Ideally, such studies would be linked to a clinical challenge. IJMS is a journal of molecular science; thus, pure clinical studies are not suited to the journal. However, clinical submissions that reflect biomolecular experiments are welcome.
Dr. Stephen Holt
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- membrane biophysics
- bilayers
- peptide
- phospholipid
- protein
- membrane protein
- self assembly
- model membranes
- glycolipids
- sterols
