Study on Post-translational Modifications of Protein
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 28 August 2024 | Viewed by 365
Special Issue Editor
Special Issue Information
Dear Colleagues,
The focus of this Special Issue is the study of post-translational protein modifications (PTMs). These modifications, such as phosphorylation, methylation, acetylation, lipidation, glycosylation, sumoylation and ubiquitinylation, which involve catalyzation by specific enzymes after protein translation, can regulate protein function in terms of activity and stability. In particular, the phosphorylation and methylation of proteins are involved in the signal transduction processes of autophagy, apoptosis and RNA metabolism. In this context, the addition of phosphate groups to specific serines or threonines often influences the binding and enzymatic activities of proteins. Proteolytic modification, such as cleavages caused by caspases during apoptosis, can also irreversibly affect protein function. All of these protein modifications play important roles in a wide variety of signaling pathways. In this Special Issue, individual PTMs as well as the interplay between different PTMs will be investigated with respect to activity, stability, localization and structural changes of the target protein.
Dr. Christoph Peter
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- phosphorylation
- methylation
- ubiquitinylation
- sumoylation
- proteolytical cleavage
