Advanced Research on Lipid Signaling Molecules
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 29 September 2024 | Viewed by 52
Special Issue Editor
Interests: endocannabinoid system; endocannabinoid quantification; endocannabinoid hydrolytic enzymes; EC hydrolytic enzyme inhibitor synthesis and characterization; MAGL, FAAH, and NAAA activity evaluation methods
Special Issue Information
Dear Colleagues,
Lipids are a key player in both extracellular and intracellular signaling in normal physiology and control numerous cellular processes, such as cell proliferation, apoptosis, metabolism, and migration, in a wide variety of tissues and cell types. Lipid signaling dysregulation contributes to inflammation, cancer, and metabolic, cardiovascular, and degenerative disease. Research promotes lipid signaling molecules being used as pharmacological tools, diagnostic or prognostic biomarkers, and, in some cases, functional nutrients and promotes their metabolic pathways as pharmacological targets. Considering the structurally diverse group of compounds composing lipid signaling molecules, such as free fatty acids, and fatty acid derivatives, such as oxylipins and eicosanoids, endocannabinoids, sphingolipids, phospholipids, and steroids, and their involvement in a wide range of physio-pathological processes, scientific research production in this area is striking.
The aim of this Special Issue is to focus on the lipid signaling molecules linked to the endocannabinoid signaling system, comprising endocannabinoids, free fatty acids, eicosanoids, and oxylipins derived from arachidonic, docosahexaenoic, and eicosatetraenoic acids, such as prostaglandins, leukotrienes, tromboxanes, resolvins, maresins, and protectins. Original research and review articles covering all aspects—such as the quantification of biomatrices in physiological and/or pathological conditions, tone modulation by enzyme activity modulation, and signaling biochemical pathways—of these families of lipid signaling molecules will be considered for publication.
Dr. Roberta Ottria
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- endocannabinoid hydrolytic enzyme inhibitors
- endocannabinoids
- oxylipins
- eicosanoids
- lipid signaling (fatty acid derivatives)
- protectins, maresins, and resolvins
