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Nutrient Sensing in Human Metabolic Diseases: Associated Molecular Mechanisms

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 30 May 2024 | Viewed by 246

Special Issue Editors

1. Department of Physiology and Biochemistry, Institute of Biology, University of Szczecin, ul. Felczaka 3c, 71-412 Szczecin, Poland
2. Chair of the Department of Functional Diagnostic and Physical Medicine, Pomeranian Medical University in Szczecin, ul. Żołnierska 54, 71-210 Szczecin, Poland.
Interests: metabolic diseases; nutrition; adaptive physiology; exercise; purine metabolism
The Institute of Biology, University of Szczecin, 71-210 Szczecin, Poland
Interests: biodiversity; genetics and genomics analysis; organellar genomes; barckoding DNA; gene expression; conservation genetics; phylogenetics; population genetics

Special Issue Information

Dear Colleagues,

One of the research areas in which modern food and nutrition sciences intersect with molecular biology is nutritional genomics, which creates a wide range opportunities to study the relationship between the genome, nutrition, and health.

Studying the impact of bioactive diet ingredients on gene expression, the relationship between diet and genetic predisposition to civilisation diseases (metabolic, cardiovascular, cancer), identification of single-nucleotide polymorphisms and alleles responsible for a differentiated response or reactions of the body to bioactive ingredients of the diet, and finally designing and recommending diets appropriate for specific individuals or populations are just some of the interests of research in nutrigenomics and nutrigenetics.

In the post-genomics era, the rapid development of molecular biology has created new research opportunities that are now full of potential and interdisciplinary character. They require the use of bioinformatics, statistical analyses and "omics" research technologies. Their area includes research on genome stability (DNA damage at the level of single genes and entire chromosomes) and epigenetic variability (e.g. DNA methylation). It can also be extended to analyse the transcriptome (including miRNA and siRNA), proteome, metabolome or microbiome. These research areas can be analyzed independently or in an integrated way, giving the opportunity to study complex interactions (systems biology). The technological developments continue, especially with regards to DNA and RNA sequencing, mass spectrometry, single-cell omics and bioinformatics.

We ask you to please join this important discussion by submitting research papers, communications and review articles on a chosen aspect of this broad topic to the special issue of the International Journal of Molecular Sciences entitled „Nutrient Sensing in Human Metabolic Diseases - Associated Molecular Mechanisms”.

Dr. Wioletta Dudzińska
Dr. Lidia Skuza
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • nutrition
  • functional food
  • bioactive compounds
  • gene
  • nutrigenomics
  • nutrigenetics
  • metabolomics
  • proteomics
  • microbiota
  • chronic diseases

Published Papers

This special issue is now open for submission.
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