Exploring Induced Pluripotent Stem Cells in Neurological Disease Modeling
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 133
Special Issue Editors
Interests: molecular neurobiology
Special Issue Information
Dear Colleagues,
The development of highly efficient models for the study of neurological diseases is instrumental in elucidating disease pathophysiology and advancing the prospects of therapeutic interventions. The discovery of the ability to reprogram somatic cells into induced pluripotent stem cells (iPSCs) has fundamentally transformed the landscape of disease modeling, particularly neurological diseases. At present, virtually all categories of neural cells, including but not limited to neurons, astrocytes, oligodendrocytes, and microglia, can be derived from iPSCs through adherence to established developmental principles. These iPSC-derived neural cells offer molecular tools for investigating the molecular mechanisms of neurological diseases, developing potential treatments, and deepening our comprehension of the nervous system.
This Special Issue aims to collect and publish the latest research trends within induced pluripotent stem cells focusing on molecular technologies developed specifically to model neurological diseases. We would like to invite authors to submit original research articles and reviews exploring the use of advanced technologies to model central and peripheral nervous systems and to study the pathogenic mechanisms and the therapeutic strategies of neurological diseases.
Dr. Arens Taga
Dr. Christa Whelan Habela
Guest Editors
Manuscript Submission Information
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Keywords
- iPSC
- neurons
- astrocytes
- microglia
- neurological diseases
- disease modeling
