Pigment Cells: From Biology to Medicine
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 42
Special Issue Editor
Interests: lomefloxacin; melanoma; oxidative stress; DNA fragmentation; apoptosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cells producing pigments have been central to scientists’ interests for years due to their biological functions and importance in medicine. Among the best-known pigmented cells are melanocytes. These specialized cells, which are mainly found in the basal layer of the epidermis, are responsible for the synthesis and epidermal distribution of the biopolymer melanin. Due to their location, cytophysiology, and biochemical characteristics, melanocytes are extremely important for maintaining skin homeostasis due to their photoprotective function and influence on redox balance. However, the exposure of melanocytes to harmful factors contributes to disturbances in their function and the induction of permanent damage. This can result in pigmentary disorders, carcinogenesis, melanoma development, and more. It should also be noted that melanin is produced outside the skin, including by retinal epithelial cells in the eyes and by some neurons in the central nervous system. This Special Issue focuses on presenting the latest discoveries regarding pigmented cells and their functions in physiological and pathophysiological states.
Dr. Jakub Rok
Guest Editor
Manuscript Submission Information
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Keywords
- melanin
- melanocyte
- melanogenesis
- melanoma
- melanosome
- neuromelanin
- photoprotection
- oxidative stress
- phototoxicity
- pigmentation disorders
- drug–melanin complexes
- skin cancer
- UV radiation
- retinal pigment epithelium
