Adenosine Receptors in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 April 2024 | Viewed by 463
Special Issue Editor
Interests: sensory systems; auditory neuroscience; inner ear diseases; inner ear therapeutics; hearing loss; inflammation; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Adenosine receptors (ARs) are essential in maintaining health, while altered AR signalling contributes to various disease processes. Adenosine acts as a cytoprotective modulator in response to stress and tissue injury, and understanding AR function is crucial for developing targeted therapies for multiple diseases.
AR signalling regulates physiological functions in the nervous, cardiovascular, and immune systems. For example, ARs regulate blood flow by inducing vasodilation, aiding tissue oxygenation, and protecting against ischemic injuries.
Dysregulation of AR signalling can lead to various pathological conditions, such as pain, cancer, neurodegenerative, inflammatory, and autoimmune diseases. In inflammatory conditions, AR modulation can either suppress or exacerbate immune responses. AR malfunction is also associated with neurological disorders such as epilepsy and Parkinson’s disease.
We invite investigators to contribute original research articles and review articles addressing the various roles of AR in physiology and pathophysiology. Please note that pure clinical or model studies are unsuitable for this journal, but clinical submissions with biomolecular studies are welcome.
Dr. Srdjan Vlajkovic
Guest Editor
Manuscript Submission Information
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Keywords
- adenosine
- adenosine receptors
- P1 receptors
- A1 receptor
- A2A receptor
- A2B receptor
- A3 receptor
- adenosine deaminase
- adenosine kinase
- adenosine transporters
- adenosine receptor agonists
- adenosine receptor antagonists
- caffeine
