Molecular Mechanisms of Cell Adhesion
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biophysics".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 71
Special Issue Editor
Interests: biomolecular NMR spectroscopy; cell adhesion; antimicrobials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cell adhesion is a pivotal physiological process in multicellular organisms including humans and animals. A set of protein families, e.g., integrins, cadherins, selectins and the immunoglobulin superfamily of proteins, is primarily involved in cell–cell and cell–matrix adhesion functions. Localized at the cell surface, these proteins contain a large extra-cellular domain, a relatively short cytosolic domain connected by a single-pass transmembrane segment. The extra-cellular domains are chiefly involved in cell–cell or cell–matrix connections, whereas transmembrane and cytosolic domains regulate the signal transduction process. In recent years, tremendous progress has been made in elucidating molecular mechanisms of many of these protein machineries by the combined use of high-resolution structures, biochemical and biophysical data and mutagenesis coupled with functional analyses. In this Special Issue, we would like to solicit in-depth review articles and original research papers in the area of cell adhesion. Additionally, the current development of drugs or therapeutics targeted to cell-adhesion complexes are of interest.
Dr. Surajit Bhattacharjya
Guest Editor
Manuscript Submission Information
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Keywords
- cell adhesion
- cell–cell communication
- structures
- drug discovery
- integrins
- cadherins
- selectins
