Natural Products in Lifestyle-Related Diseases: Molecular Mechanisms, Prevention and Treatments
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 August 2024 | Viewed by 74
Special Issue Editor
Interests: traditional medicine; lifestyle-related diseases; advanced glycation end-products
Special Issue Information
Dear Colleagues,
Lifestyle-related diseases (LSRDs), including diabetes mellitus (DM), cardiovascular disease (CVD), non-alcoholic hepatosteatosis (NASH), cancer, sarcopenia, and Alzheimer's disease (AD), are major issues worldwide. Many researchers have analyzed the mechanisms of LSRDs based on molecular research and their prevention/treatment methods have been explored.
Recently, natural products have gained focus due to their ability to prevent and cure LSRDs. Although natural products’ mechanisms of prevention/treatment are yet to be thoroughly analyzed in order to provide evidence at the molecular level or a basis in molecular science, known effects are involved for some LSRDs (e.g., DM, CVD, and NASH) that Western medicine (modern medicine) is unable to effectively employ. Extracts from plants, animals, and minerals are used to compile natural products. In medicinal history, various components (e.g., low-molecular-weight compounds, polysaccharides, and proteins) were isolated from natural products and proven to treat certain LSRDs. However, evidence regarding the mechanisms through which they are able to do so is difficult to come by, because crude drugs contain various compounds that should be delivered via oral administration, where their various compounds are digested, absorbed, and metabolized, leading to the occurrence of various phenomena for the body’s organs. Therefore, these factors should be explored experimentally both in vitro and in vivo regarding natural products’ mechanisms of action towards LSRDs, the analyses of which should be grounded in molecular-level research in order to pioneer 21st century medicine.
Dr. Takanobu Takata
Guest Editor
Manuscript Submission Information
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Keywords
- natural products
- crude drugs
- lifestyle-related diseases
- diabetes mellitus
- cardiovascular disease
- non-alcoholic hepatosteatosis
- cancer
- sarcopenia
- Alzheimer’s disease
