Zinc in the Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 20 July 2024 | Viewed by 93
Special Issue Editor
Interests: zinc; platelets; zinc homeostasis; haemostasis; wound healing; zinc signalling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent decades, the role of zinc as a critically important element in the maintenance of health and in disease progression has been established. Dietary zinc is essential for health, growth, and development, and dietary deficiency results in a range of symptoms including immune suppression, dermatitis, diarrhoea, and defects in wound healing, and it can also be a contributing factor to the severity of infectious diseases. Supplementation of the diet with zinc is beneficial in a number of conditions and has been reported to increase survival rates during COVID-19 infection. Zinc has numerous biological roles, for example as a structural component in proteins or catalytic component of enzymes, and as a signalling element. It also plays roles in the immune system, during oxidative stress and apoptosis, during haemostasis, in wound healing, and in the ageing process. Zinc toxicity has necessitated the evolution of homeostatic control mechanisms, the importance of which is exemplified by Acrodermatitis enteropathica, where mutations of a zinc transporter disrupt zinc homeostasis.
In this Special Issue, we welcome a range of contributions, including original papers and reviews, to further clarify the roles of zinc in health and disease.
Dr. Nicholas Pugh
Guest Editor
Manuscript Submission Information
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Keywords
- zinc
- zinc homeostasis
- dietary zinc deficiency
- zinc disorders
- zinc signalling
