Advanced Research on Protein Structure and Protein Dynamics
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 76
Special Issue Editor
Interests: cystic fibrosis; protein folding and quality control; protein trafficking; chaperones
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Proteins are critical “workhorses” in the cells of all living organisms and are essential for a variety of processes, such as signal transduction, cell division, and metabolic pathways. Biophysical and biochemical studies have revealed that proteins are not static entities but are subject to dramatic molecular movements that span from femtosecond vibrations of atoms to slow motions of domains that can last for micro-to-milliseconds. The field of protein dynamics endeavors to study these complex molecular motions. Advances in biophysical and computational techniques are providing new insights into these protein structural changes. For example, the use of cryogenic-electron microscopy (cryo-EM) has led to greater insight into the molecular motions of G-protein coupled receptors upon ligand binding and activation. Combining structural studies with molecular dynamic simulations has been instrumental in investigating the protein folding problem and led to new hypotheses and avenues of research. The latest generation of computing hardware combined with artificial intelligence (AI) promises to advance the field of protein dynamics.
Researchers that utilize biophysical (e.g., cryo-EM, X-ray crystallography, NMR), biochemical (e.g., Fluorescence Fluctuation Techniques), or computational techniques (e.g., molecular dynamic simulations) applied to any domain of cell and molecular biology are welcome to submit their work for consideration. This Special Issue aims to showcase original research articles, reviews, mini-reviews, and commentaries describing the current knowledge of protein dynamics and the protein structural changes that contribute to these molecular movements.
Dr. Robert T. Youker
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- allostery
- receptor
- kinase
- protein folding
- simulations
- X-ray crystallography
- NMR
- super-resolution imaging
- fluorescence fluctuation techniques
- thermodynamic
- enzyme
- catalysis
- artificial intelligence
