Molecular Advances in Alzheimer’s Disease 3.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 21
Special Issue Editor
Interests: Alzheimer’s disease; Parkinson’s disease; biomarkers; protein’s deposition; neuroinflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alzheimer’s disease (AD), the most common cause of dementia among the elderly, is characterized by loss of memory and other cognitive functions. The main neuropathological changes associated with AD include synaptic and neuronal loss, astrogliosis, and protein deposition. Despite these neuropathological hallmarks, emerging data suggest that the disease has a complex aetiology; neuroinflammation, oxidative stress, and mitochondrial dysfunction seem to play an important role in the pathophysiology of mild cognitive impairment and AD, as well as in other neurodegenerative disorders such as Parkinson’s disease. However, the underlying molecular mechanisms associated with these alterations are still elusive. Unfortunately, AD diagnosis occurs at a stage in which the underlying pathology has reached an advanced and possibly irreversible state. Therefore, the major challenges in AD research are to identify biomarkers for early diagnosis and finding therapeutic strategies that prevent the development of the pathology. For that, we need to decipher the cellular and molecular mechanisms that underlie AD and other neurodegenerative diseases, as well as their progression and severity.
This Special Issue will focus on reviews and original data manuscripts that concern (1) the molecular mechanism of Alzheimer’s and other neurodegenerative diseases; (2) molecular targets for new Alzheimer’s biomarkers; (3) the genetics of Alzheimer’s and other neurogenerative diseases; (4) molecular targets for new therapeutic techniques for Alzheimer’s; (5) the molecular mechanism of neuroinflammation in neurodegenerative diseases.
Dr. María-Salud García-Ayllón
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- molecular targets
- neurodegenerative diseases
- Alzheimer’s disease
- Parkinson’s
- neuroinflammation
