Recent Research of Chemokines in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 15 June 2024 | Viewed by 138
Special Issue Editor
Interests: metallomics; neurotoxicology; neurobiochemistry and molecular biology of heavy metals
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chemokines are almost 50 chemotactic cytokines whose first discovered properties were the chemotactic effect on cells of the immune system. With the progress of knowledge, a significant role of chemokines in the regulation of the functioning of cells of the immune system has been found. Thus, the involvement of chemokines in many diseases, in the pathogenesis of which there is a dysregulated immune system, has been demonstrated. Also, chemokines act on non-immune cells. An example of this is the effect on endothelial cells, which causes migration, proliferation and, consequently, angiogenesis. The second example is the effect of chemokines on cancer cells, which leads to their migration and invasion as well as may increase the proliferation of cancer cells. Another example is the effect of chemokines on hepatocytes, which causes an increase in collagen production, which is one of the symptoms of cirrhotic liver. Chemokines are of great importance in the functioning of a healthy body as well as in the pathogenesis of many diseases. For this reason, they are extensively studied.
Prof. Dr. Irena Baranowska-Bosiacka
Guest Editor
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Keywords
- chemokines
- inflammation
- cancer
- infection
- angiogenesis
- fibrosis
- hematopoiesis
