Molecular Research of Alzheimer’s Disease and Nutrition Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 70
Special Issue Editors
Interests: neuropharmacology; neurobiology; neurotransmitter release; presynaptic receptors; Alzheimer's disease; cAMP/cGMP-Abeta/Tau signalling in memory
Special Issues, Collections and Topics in MDPI journals
Interests: Alzheimer’s disease, animal behaviour, receptor-receptor interaction, nicotinic receptors, muscarinic receptors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alzheimer’s disease (AD) is the most prevalent form of dementia worldwide with aging representing the main risk factor. There is now a large consensus indicating that the sporadic form of AD has a multifactorial nature in which genetic, environmental and lifestyle factors play key roles. Unfortunately, there are no effective therapies for AD, and therefore, attention needs to be paid to prevention strategies that could significantly impact on the evolution of this neurodegenerative disease. In this view, a large body of evidence suggests that equilibrated and integrated nutrition can be of great importance for healthy aging of the brain as well as of other organs, whereas bad dietary habits can significantly increase the risk of developing CNS diseases, including dementia.
Moreover, the research of the last fifteen years has brought into the limelight how a dysregulation of the gut–brain axis can contribute to molecular and cellular mechanisms that lead to neurodegenerative disorders.
The aim of this Special Issue is to collect original research articles and reviews that can extend and update our knowledge on the influence of nutrition in triggering or preventing synapto/neurotoxic events that could be responsible for or participate in the pathophysiology of AD.
We look forward to receiving your contributions.
Prof. Dr. Ernesto Fedele
Dr. Massimo Grilli
Guest Editors
Manuscript Submission Information
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Keywords
- Alzheimer’s disease
- nutrition
- supplements
- gut–brain axis
- microbiome
- β-amyloid
- tau protein
- neuroinflammation
- excitotoxicity
