Current Developments in Glioblastoma Research and Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 June 2024 | Viewed by 253
Special Issue Editor
Interests: brain tumors; glioblastoma; epigenetics; pharmacoepigenetics; biomarkers; Wnt/β-catenin pathway; phytocompounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Glioblastoma remains one of the most aggressive and incurable malignancies. Even after the standard treatment, consisting of surgery, radiotherapy, and chemotherapy, tumor recurrence is only a matter of time and the prognosis for glioblastoma patients is still very poor. Therefore, rapid progress in developing a better understanding of glioblastoma pathogenesis and recurrence is needed and novel ways to improve patient outcomes are desperately required.
Fortunately, glioblastoma research is thriving, and new approaches towards the more precise diagnosis and effective therapy of this deadly disease are constantly being evaluated. The implementation of combinatorial therapies, immunotherapy, and nanomedicine are several of the examples of strategies tested in order to surpass the current obstacles in glioblastoma treatment.
The aim of this Special Issue is to collect the most recent discoveries regarding glioblastoma research, ranging from molecular mechanisms to therapeutic approaches. All advancements in characterizing GBM pathogenesis, including genomic, epigenomic, transcriptomic, and proteomic analyses of GBM cells, are of interest in this Special Issue. Moreover, we welcome the evaluation of innovative therapeutic agents and new treatment approaches.
We invite authors to submit original preclinical, translational, and clinical works, as well as review articles regarding the above-mentioned cutting-edge topics, to this Special Issue of International Journal of Molecular Sciences.
We are looking forward to your contributions.
Dr. Aleksandra Majchrzak-Celińska
Guest Editor
Manuscript Submission Information
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Keywords
- diagnostic, prognostic and predictive biomarkers of glioblastoma
- ways to target glioma stem cells
- targeting glioblastoma-related signaling pathways
- epigenetics of glioblastoma
- treatment resistance mechanisms
- novel treatment options for glioblastoma
- combinatorial therapies
- immunotherapy
- nanotherapy
- the application of CRISPR/Cas9 in glioma research
- molecular testing of long-term glioblastoma survivors
