Immune Modulation of Macrophages 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 30 May 2024 | Viewed by 224
Special Issue Editors
2. Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Interests: genetics and development biology of birth defects; genomics of childhood tumors; immunology and inflammation
Special Issues, Collections and Topics in MDPI journals
2. Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Interests: immunology and inflammation in birth defects and tumors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
A macrophage is a multifunctional cell type presenting consistent phenotype changes over its lifespan beginning from the embryonic period. The differentiation and maturation dependent on the microenvironment and in response to the internal and external stimuli often result in the heterogenicity of the cells, by which the interpretation of the function becomes difficult. As a result, therapeutic treatment in cell targeting has frequently been ineffective. With the increased knowledge provided by updated forms of technology, especially multi-omics and spatial transcriptomic technologies, the functional understanding of macrophages in both physiological and pathological conditions in different tissues and organs is becoming increasingly advanced. In line with the creation of new technologies, the modulation of the cells in different pathological conditions, such as cancer, in response to the different drugs or reagents for different diseases during the development stages will provide a novel phenotypical assessment. A good understanding of the alternating functions of macrophages will help scientists to develop new strategies in terms of precision or personalized therapies in treating diseases.
This Special Issue entitled “Immune Modulation of Macrophages 2.0” invites submissions of original reviews in this field of research, and focuses on the advanced technology concerning the understanding of the heterogenicity of cells in the disease process, especially in the phenotype changes and pathway analysis in response to the external treatment in disease treatments.
Prof. Dr. Paul Kwong Hang Tam
Dr. Yan Chen
Guest Editors
Manuscript Submission Information
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Keywords
- macrophages
- treatment
- phenotype change
- pathway analysis
