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Pharmacological Treatment of Neuroinflammation

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 30 August 2024 | Viewed by 113

Special Issue Editor


E-Mail Website
Guest Editor
Department of Pathology, University of Pisa, 56126 Pisa, Italy
Interests: neuroscience; Alzheimer’s disease; neuroinflammation

Special Issue Information

Dear Colleagues,

Neuroinflammation is a critical pathophysiological process that plays a central role in the development and progression of neurodegenerative diseases (NDDs). Several studies have suggested that in NDDs (including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis), inflammation is not only a result of neurodegeneration but also a crucial player in this process. In the central nervous system, effectors of inflammatory response are immune cell systems as well as glial cells and, mainly, microglia cells. Particularly, microglia act as sensors for disturbed brain tissue homeostasis and accumulate locally in response to neuronal cell injury or foreign entry in the brain. The differential activation of microglia is the central point that regulates neuroinflammation, and it can result in neurotoxicity or neuroprotection.

Based on these considerations, the therapeutic modulation of glial activation and consequent neuroinflammation could represent valid candidates for the treatment or prevention of common NDDs.

Dr. Beatrice Polini
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microglia
  • neuroinflammation
  • neurodegeneration
  • Alzheimer’s disease
  • Parkinson’s disease
  • therapeutic
  • natural molecules

Published Papers

This special issue is now open for submission.
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