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Molecular Bioinformatics in Pediatric Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Informatics".

Deadline for manuscript submissions: 29 July 2024 | Viewed by 67

Special Issue Editor


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Guest Editor
Clinical Bioinformatics Unit, IRCCS Istituto Giannina Gaslini, 5-16147 Genova, Italy
Interests: bioinformatics; machine learning; epigenetics; molecular epidemiology; DNA methylation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Pediatric diseases include a large set of disorders affecting children from birth to adolescence. Understanding the underlying molecular mechanisms of these diseases is crucial for developing effective diagnostic tools and therapeutic interventions. Bioinformatics, machine learning, and artificial intelligence have revolutionized pediatric medicine by providing powerful tools to analyze complex biomolecular data and gain insights into disease pathogenesis.

This Special Issue aims to highlight the new developments and applications of bioinformatics methods in pediatric research, including the importance of deciphering the crucial role of in utero and early-life exposures in shaping pediatric and adult health outcomes. We invite researchers to submit manuscripts addressing the following critical areas:

  1. Genome-wide association studies for the identification of genetic variants associated with pediatric diseases.
  2. Development of predictive models for disease risk, treatment response, and clinical outcomes using machine learning and artificial intelligence, with a focus on pediatric diseases and incorporating the impact of early-life exposures.
  3. Elucidating the molecular mechanisms linking in utero and early-life exposures to future disease development using comprehensive omics data (epigenomic, transcriptomic, proteomic, metabolomic, and gut microbiome), with a focus on pediatric populations.
  4. Development of personalized medicine approaches for pediatric patients.

We encourage submissions of original research articles that highlight the potential of bioinformatics in improving the molecular-level understanding and management of pediatric diseases, emphasizing the profound impact of in utero and early-life exposures on shaping future health trajectories.

Dr. Giovanni Fiorito
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pediatric diseases
  • bioinformatics
  • in utero and early-life exposures
  • multi-omic biomarkers
  • personalized medicine

Published Papers

This special issue is now open for submission.
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